Biomarkers in diabetic retinopathy

AJ Jenkins, MV Joglekar, AA Hardikar… - The review of …, 2015 - pmc.ncbi.nlm.nih.gov
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Essential role of multi-omics approaches in the study of retinal vascular diseases

Y Lei, J Guo, S He, H Yan - Cells, 2022 - mdpi.com
Retinal vascular disease is a highly prevalent vision-threatening ocular disease in the global
population; however, its exact mechanism remains unclear. The expansion of omics …

Lutein attenuates both apoptosis and autophagy upon cobalt (II) chloride-induced hypoxia in rat Műller cells

FKC Fung, BYK Law, ACY Lo - PloS one, 2016 - journals.plos.org
Retinal ischemia/reperfusion injury is a common feature of various retinal diseases such as
glaucoma and diabetic retinopathy. Lutein, a potent anti-oxidant, is used to improve visual …

Retinal proteomics of experimental glaucoma model reveal intraocular pressure‐induced mediators of neurodegenerative changes

M Mirzaei, VK Gupta, N Chitranshi… - Journal of cellular …, 2020 - Wiley Online Library
Current evidence suggests that exposure to chronically induced intraocular pressure (IOP)
leads to neurodegenerative changes in the inner retina. This study aimed to determine …

Large-scale protein analysis of experimental retinal artery occlusion

N Vestergaard, LJ Cehofski, AN Alsing, A Kruse… - International Journal of …, 2023 - mdpi.com
Retinal artery occlusion (RAO) is a devastating condition with no effective treatment. The
management of RAO could potentially be improved through an in-depth understanding of …

Overexpression of glyceraldehyde 3‐phosphate dehydrogenase prevents neurovascular degeneration after retinal injury

R Cai, W Xue, S Liu, RB Petersen, K Huang… - The FASEB …, 2015 - Wiley Online Library
Ischemia and reperfusion (I/R) injury is a common cause of many vascular and neuronal
diseases. Glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) has been found down …

Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases

Z Meng, R You, A Mahmood, F Yan, Y Wang - Brain Sciences, 2023 - mdpi.com
Optic nerve damage is a common cause of blindness. Optic nerve injury is often
accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in …

[PDF][PDF] Retinal artery occlusion-Experimental and epidemiological studies

NV Azuz - 2023 - vbn.aau.dk
Retinal artery occlusion (RAO) is a devastating disorder that frequently leads to severe
vision loss in the affected eye. Most often induced by embolism, RAO shares similarities with …

Neuroserpin, a Serine Protease Inhibitor Providing Neuroprotection in the Retina

R Rajput - figshare.mq.edu.au
In glaucoma, loss of retinal ganglion cells (RGCs) and axons leads to blindness, and
preservation of RGCs is a major therapeutic goal. High intraocular pressure (IOP) has been …

Experimental glaucoma retinal proteomics identifies mutually exclusive and overlap** molecular characteristics with human glaucoma

M Mirzaei, V Gupta, N Chitranshi, L Deng, K Pushpitha… - bioRxiv, 2020 - biorxiv.org
Current evidence suggests that exposure to chronically induced intraocular pressure (IOP)
leads to neurodegenerative changes in the inner retina. This study aimed to determine …