Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

Male infertility is a widely debated issue that affects males globally. There are several
mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with …

In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

Objective To identify the most robust molecular biomarkers in sperm and seminal plasma for
the diagnosis of male infertility, and to evaluate their clinical use. Design Systematic review …

Abstract STUDY QUESTION Are exosomal microRNAs (miRNAs) in seminal plasma (SP)
useful as markers of the origin of azoospermia and the presence of sperm in the testis …

Background The presence of miRNAs in human reproductive tissue is intriguing and
suggests the possibility that these important regulatory molecules play a role in reproductive …

Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

The World Health Organization predicts that infertility will be the third major health threat
after cancer and cardiovascular disease, and will become a hot topic in medical research …

Objective To validate a set of five microRNAs (miRNAs) as specific biomarkers for the
assessment of male infertility. Design Quantitative real-time polymerase chain reaction (qRT …