Advancing organoid engineering for tissue regeneration and biofunctional reconstruction

H **, Z Xue, J Liu, B Ma, J Yang, L Lei - Biomaterials Research, 2024 - spj.science.org
Tissue damage and functional abnormalities in organs have become a considerable clinical
challenge. Organoids are often applied as disease models and in drug discovery and …

Engineering considerations of iPSC-based personalized medicine

S Park, Y Gwon, SA Khan, KJ Jang, J Kim - Biomaterials Research, 2023 - spj.science.org
Personalized medicine aims to provide tailored medical treatment that considers the clinical,
genetic, and environmental characteristics of patients. iPSCs have attracted considerable …

[HTML][HTML] Newer approaches to dry eye therapy: Nanotechnology, regenerative medicine, and tissue engineering

VP Joshi, S Singh, M Thacker, F Pati… - Indian journal of …, 2023 - journals.lww.com
Definitive treatment of dry eye disease (DED), one of the commonest ocular surface
disorders, has remained elusive despite several recent advances in better diagnostics and …

Dental pulp stem cells for the study of neurogenetic disorders

AK Victor, LT Reiter - Human molecular genetics, 2017 - academic.oup.com
Dental pulp stem cells (DPSC) are a relatively new alternative stem cell source for the study
of neurogenetic disorders. DPSC can be obtained non-invasively and collected from long …

Diversity of dermal fibroblasts as major determinant of variability in cell reprogramming

AM Sacco, I Belviso, V Romano… - Journal of Cellular …, 2019 - Wiley Online Library
Induced pluripotent stem cells (iPSCs) are adult somatic cells genetically reprogrammed to
an embryonic stem cell‐like state. Notwithstanding their autologous origin and their potential …

Potential of mesenchymal stem cells as topical immunomodulatory cell therapies for ocular surface inflammatory disorders

LJ Beeken, DSJ Ting, LE Sidney - Stem Cells Translational …, 2021 - academic.oup.com
Ocular surface inflammatory disorders (OSIDs) are a group of highly prevalent,
heterogeneous diseases that display a variety of aetiologies and symptoms and are risk …

Standardisation is the key to the sustained, rapid and healthy development of stem cell‐based therapy

J Zhang, M Suo, J Wang, X Liu, H Huang… - Clinical and …, 2024 - Wiley Online Library
Background Stem cell‐based therapy (SCT) is an important component of regenerative
therapy that brings hope to many patients. After decades of development, SCT has made …

Rapid differentiation of human dental pulp stem cells to neuron-like cells by high K+ stimulation

Y Kogo, C Seto, Y Totani, M Mochizuki… - Biophysics and …, 2020 - jstage.jst.go.jp
As human-origin cells, human dental pulp stem cells (hDPSCs) are thought to be potentially
useful for biological and medical experiments. They are easily obtained from lost primary …

Organoids and their research progress in plastic and reconstructive surgery

H Wu, G Wang, Y Shang, N Liu, Y Zhen, L Chen… - Aesthetic Plastic …, 2023 - Springer
Organoids are 3D structures generated from stem cells. Their functions and physiological
characteristics are similar to those of normal organs. They are used in disease mechanism …

The role of the reprogramming method and pluripotency state in gamete differentiation from patient-specific human pluripotent stem cells

S Mishra, E Kacin, P Stamatiadis… - MHR: Basic science …, 2018 - academic.oup.com
The derivation of gametes from patient-specific pluripotent stem cells may provide new
perspectives for genetic parenthood for patients currently facing sterility. We use current data …