Natural killer cell integrins and their functions in tissue residency

MJ Shannon, EM Mace - Frontiers in Immunology, 2021 - frontiersin.org
Integrins are transmembrane receptors associated with adhesion and migration and are
often highly differentially expressed receptors amongst natural killer cell subsets in …

Reversal of immunity after clearance of chronic HCV infection—all reset?

H Wedemeyer, T Khera, B Strunz… - Frontiers in …, 2020 - frontiersin.org
Chronic viral infections cause deterioration of our immune system. However, since persistent
infections rarely can be eliminated, the reinvigoration capacity of an exhausted immune …

A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses

V Stary, RV Pandey, J Strobl, L Kleissl… - Science …, 2020 - science.org
Adaptive features of natural killer (NK) cells have been reported in various species with
different underlying mechanisms. It is unclear, however, which NK cell populations are …

Full spectrum flow cytometry and mass cytometry: A 32‐marker panel comparison

MC Jaimes, M Leipold, G Kraker, E Amir… - Cytometry Part …, 2022 - Wiley Online Library
High‐dimensional single‐cell data has become an important tool in unraveling the
complexity of the immune system and its involvement in homeostasis and a large array of …

Chemogenomic screening in a patient‐derived 3D fatty liver disease model reveals the CHRM1‐TRPM8 axis as a novel module for targeted intervention

S Youhanna, AM Kemas, SC Wright, Y Zhong… - Advanced …, 2025 - Wiley Online Library
Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of chronic liver
disease with few therapeutic options. To narrow the translational gap in the development of …

The liver as an immunological barrier redefined by single‐cell analysis

Z Stamataki, L Swadling - Immunology, 2020 - Wiley Online Library
The liver is a front‐line immune tissue that plays a major role in the detection, capture and
clearance of pathogens and foreign antigens entering the bloodstream, especially from the …

Tissue-specific nonheritable influences drive endometrial immune system variation

J Bister, I Filipovic, D Sun, Y Crona-Guterstam… - Science …, 2024 - science.org
Although human twin studies have revealed the combined contribution of heritable and
environmental factors in sha** immune system variability in blood, the contribution of …

Considerations of antibody geometric constraints on NK cell antibody dependent cellular cytotoxicity

CD Murin - Frontiers in Immunology, 2020 - frontiersin.org
It has been well-established that antibody isotype, glycosylation, and epitope all play roles in
the process of antibody dependent cellular cytotoxicity (ADCC). For natural killer (NK) cells …

Regulation of MHC I molecules in glioblastoma cells and the sensitizing of NK cells

T Burster, F Gärtner, C Bulach, A Zhanapiya, A Gihring… - Pharmaceuticals, 2021 - mdpi.com
Immunotherapy has been established as an important area in the therapy of malignant
diseases. Immunogenicity sufficient for immune recognition and subsequent elimination can …

Monitoring of the forgotten immune system during critical illness—A narrative review

MA Serrano, AMC Gomes, SM Fernandes - Medicina, 2022 - mdpi.com
Immune organ failure is frequent in critical illness independent of its cause and has been
acknowledged for a long time. Most patients admitted to the ICU, whether featuring infection …