Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

Can the “female protective effect” liability threshold model explain sex differences in autism spectrum disorder?

JD Dougherty, N Marrus, SE Maloney, B Yip, S Sandin… - Neuron, 2022 - cell.com
Male sex is a strong risk factor for autism spectrum disorder (ASD). The leading theory for a"
female protective effect"(FPE) envisions males and females have" differing thresholds" …

The relationship between autism and ehlers-danlos syndromes/hypermobility spectrum disorders

EL Casanova, C Baeza-Velasco, CB Buchanan… - Journal of personalized …, 2020 - mdpi.com
Considerable interest has arisen concerning the relationship between hereditary connective
tissue disorders such as the Ehlers-Danlos syndromes (EDS)/hypermobility spectrum …

Endophenotype trait domains for advancing gene discovery in autism spectrum disorder

MW Mosconi, CJ Stevens, KE Unruh, R Shafer… - Journal of …, 2023 - Springer
Autism spectrum disorder (ASD) is associated with a diverse range of etiological processes,
including both genetic and non-genetic causes. For a plurality of individuals with ASD, it is …

[HTML][HTML] Prenatal exposure to benzodiazepines and Z-drugs in humans and risk of adverse neurodevelopmental outcomes in offspring: A systematic review

X Wang, T Zhang, I Ekheden, Z Chang… - Neuroscience & …, 2022 - Elsevier
When used during pregnancy, benzodiazepines (BZDs) and related z-drugs could pass
readily through the placenta and the foetal blood-brain barrier, where they can bind to γ …

[HTML][HTML] Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review

NF Parrella, AT Hill, LM Dipnall, YJ Loke… - Journal of Psychiatric …, 2024 - Elsevier
The primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) has a prominent role in
regulating neural development and function, with disruption to GABAergic signalling linked …

Clinical autism subscales have common genetic liabilities that are heritable, pleiotropic, and generalizable to the general population

TR Thomas, T Koomar, LG Casten, AJ Tener… - Translational …, 2022 - nature.com
The complexity of autism's phenotypic spectra is well-known, yet most genetic research uses
case-control status as the target trait. It is undetermined if autistic symptom domain severity …

Modality-specific associations between sensory differences and autistic traits

P Bang, K Igelström - Autism, 2023 - journals.sagepub.com
Sensory processing differences measured by self-or parent-report co-segregate with
quantitative autistic traits and have potential endophenotypic properties. It is not known to …

A constellation of eye-tracking measures reveals social attention differences in ASD and the broad autism phenotype

K Nayar, F Shic, M Winston, M Losh - Molecular Autism, 2022 - Springer
Background Social attention differences, expressed through gaze patterns, have been
documented in autism spectrum disorder (ASD), with subtle differences also reported among …

Exploring the genetics of rhythmic perception and musical engagement in the Vanderbilt Online Musicality Study

DE Gustavson, PL Coleman, Y Wang… - Annals of the new …, 2023 - Wiley Online Library
Uncovering the genetic underpinnings of musical ability and engagement is a foundational
step for exploring their wide‐ranging associations with cognition, health, and …