Background and purpose: The regulatory guidelines (ICHS7B) recommending inhibition of
the delayed rectifier K+ current (IKr), carried by human ether‐a‐go‐go‐related gene (hERG) …

The medial nucleus of the trapezoid body (MNTB) is specialized for high frequency firing by
expression of Kv3 channels, which minimize action potential (AP) duration, and Kv1 …

The xCELLigence real time cell analyzer Cardio system offers a new system for real-time
cell analysis that measures impedance-based signals in a label-free noninvasive manner …

Human Ether-à-go-go (hERG) channels contribute to cardiac repolarization, and inherited
variants or drug block are associated with long QT syndrome type 2 (LQTS2) and …

Human ether-à-go-go related gene (hERG) K+ channels are important in cardiac
repolarization, and their dysfunction causes prolongation of the ventricular action potential …

Rationale: The human ether-a-go-go–related gene (hERG) encodes the α subunit of the
potassium current I Kr. It is highly expressed in cardiomyocytes and its mutations cause long …

Activators of the human ether-a-go-go-related gene (hERG) K+ channel have been reported
recently to enhance hERG current amplitude (five synthetic small molecules and one …

Introduction 3. Genetic manipulation of channel function in the mice 3.1. Functional
consequences of targeting Ito and IK in the mouse 3.2. Voltage-gated channels underlying …

Action potential voltage-clamp (APVC) is a technique to visualize the profile of various
currents during the cardiac action potential. This review summarizes potential applications …

Voltage-gated eag-related gene (Erg) K+ channels regulate the electrical activity of many
cell types. Data regarding Erg channel expression and function in electrically excitable …