Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative disorders.
Their etiologies are idiopathic, and treatments are symptomatic and orientated towards …

Despite considerable research to uncover them, the anatomic and neuropathologic
correlates of memory impairment in dementia with Lewy bodies (DLB) remain unclear. While …

Background: Parkinson's disease (PD) is a prevalent neurodegenerative disease that is
pathologically described as a six-stage α-synucleinopathy. In stage 4, α-synuclein reaches …

Background: The characteristic progression of Lewy pathology in Parkinson's disease likely
involves intercellular exchange and the accumulation of misfolded α‐synuclein amplified by …

The hippocampus has a critical role in cognition and human memory and is one of the most
studied structures in the brain. Despite more than 400 years of research, little is known about …

CA2 is probably the most enigmatic of the hippocampal fields. It is small in size (in humans
about 500 μm across the mediolateral axis), and yet, it is involved in important functions …

Background α-synucleinopathy emerges quite early in olfactory structures such as the
olfactory bulb and anterior olfactory nucleus (OB/AON) in Parkinson's disease. This may …

Recent post-mortem studies reported 22–37% of patients with multiple system atrophy can
develop cognitive impairment. With the aim of identifying associations between cognitive …

Abstract α-Synuclein (αSyn) is central to the neuropathology of Parkinson's disease (PD)
due to its propensity for misfolding and aggregation into neurotoxic oligomers …