Scientific interest in temporary diaphragm neurostimulation has dramatically evolved in the
last few years. Despite a solid physiological rationale and promising preliminary findings …

Pulmonary air leaks are amongst the most common complications in lung surgery. Lung
sealants are applied to the organ surface and need to synchronously stretch with the …

Background Common respiratory illnesses, such as emphysema and chronic obstructive
pulmonary disease, are characterized by connective tissue damage and remodeling. Two …

Tissue remodeling in pulmonary disease irreversibly alters lung functionality and impacts
quality of life. Mechanical ventilation is amongst the few pulmonary interventions to aid …

Distal airways commonly obstruct in lung disease and despite their importance, their
mechanical properties are vastly underexplored. The lack of bronchial experiments restricts …

Recent years have seen the development of multiple in silico lung models, notably with the
aim of improving patient care for pulmonary diseases. These models vary in complexity and …

Understanding the dynamic pathogenesis and treatment response in pulmonary diseases
requires probing the lung at cellular resolution in real time. Despite advances in intravital …

Conflicts of Interest: DWK is a co-founder and shareholder of OscillaVent, Inc., and is
coinventors on a patent involving multi-frequency oscillatory ventilation. DWK also receives …

Increased ventilator use during the COVID-19 pandemic resurrected persistent questions
regarding mechanical ventilation including the difference between physiological and …

The lung comprises multiple components including the parenchyma, airways, and visceral
pleura, where each constituent displays specific material properties that together govern the …