Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …

Calcitonin-gene-related peptide (CGRP) plays a key role in migraine pathophysiology and
more specifically in the mechanisms underlying peripheral and central sensitization. Here …

In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

Chronic pain is a major public health issue with an incidence of 20–25% worldwide that can
take different forms like neuropathic, cancer-related or inflammatory pain. Chronic pain often …

Objective/Background Migraine is associated with ischemic stroke. Women are 3‐fold as
likely as men to have migraine, and high estrogen states increase the risk of migraine with …

Alterations in the neuro-immune balance play a major role in the pathophysiology of chronic
neuropathic pain. MicroRNAs (miRNA) can regulate both immune and neuronal processes …

The calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of several
pain-related syndromes, including migraine. Targeting CGRP and its receptor by their …

Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …