[HTML][HTML] Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

RK Chinnadurai, N Khan, GK Meghwanshi… - Biomedicine & …, 2023 - Elsevier
The escalating rate of cancer cases, together with treatment deficiencies and long-term side
effects of currently used cancer drugs, has made this disease a global burden of the 21st …

Zinc oxide nanoparticles functionalized with cinnamic acid for targeting dental pathogens receptor and modulating apoptotic genes in human oral epidermal …

OV Ravikumar, V Marunganathan, MSK Kumar… - Molecular Biology …, 2024 - Springer
Background Oral diseases are often attributed to dental pathogens such as S. aureus, S.
mutans, E. faecalis, and C. albicans. In this research work, a novel approach was employed …

Marine-derived κ-carrageenan-coated zinc oxide nanoparticles for targeted drug delivery and apoptosis induction in oral cancer

V Marunganathan, MSK Kumar, ZA Kari, J Giri… - Molecular Biology …, 2024 - Springer
Background Kappaphycus alvarezii, a marine red algae species, has gained significant
attention in recent years due to its versatile bioactive compounds. Among these, κ …

Mechanistic interplay of dual environmental stressors: Bisphenol-A and cadmium-induced ovarian follicular damage and hepatocyte dysfunction in vivo

G Sudhakaran, PS Priya, B Haridevamuthu… - Science of the Total …, 2024 - Elsevier
This study investigates the individual and combined toxic effects of Bisphenol A (BPA) and
Cadmium (Cd) in zebrafish, recognizing the complex mixture of pollutants organisms …

Food peptidomic analysis of bovine milk fermented by Lacticaseibacillus casei LBC 237: In silico prediction of bioactive peptides and anticancer potential

EH Bellaver, EE Redin, IM da Costa, LS Moroni… - Food Research …, 2024 - Elsevier
Bioactive peptides, which exhibited diverse biological activities such as anti-cancer, anti-
inflammatory, bactericidal, antiviral, and quorum sensing properties, were considered …

Skeletal and neurological risks demonstrated in zebrafish due to second-hand cigarette smoke and the neutralization of luteolin

G Sudhakaran, AR Sreekutty, S Subramaniyan… - Tissue and Cell, 2023 - Elsevier
Background Cigarette smoke exposure poses significant health risks, including oxidative
stress, inflammation, tissue damage, and neurodegenerative diseases. Luteolin, a natural …

Brain targeted luteolin-graphene oxide nanoparticle abrogates polyethylene terephthalate induced altered neurological response in zebrafish

A Guru, R Murugan, BO Almutairi, S Arokiyaraj… - Molecular Biology …, 2024 - Springer
Background Polyethylene terephthalate (PET), a commonly used polymer in various food
and plastic bag containers, has raised significant concerns regarding its environmental and …

Discovery of anticancer peptides from natural and generated sequences using deep learning

J Yue, T Li, J Xu, Z Chen, Y Li, S Liang, Z Liu… - International Journal of …, 2025 - Elsevier
Anticancer peptides (ACPs) demonstrate significant potential in clinical cancer treatment
due to their ability to selectively target and kill cancer cells. In recent years, numerous …

Nimbin (N1) and analog N3 from the neem seeds suppress the migration of osteosarcoma MG-63 cells and arrest the cells in a quiescent state mediated via …

G Sudhakaran, M Velayutham, NH Aljarba… - Molecular Biology …, 2023 - Springer
Background Natural products are considered effective sources for new therapeutic research
and development. The numerous therapeutic properties of natural substances in traditional …

Delineating the protective action of cordycepin against cadmium induced oxidative stress and gut inflammation through downregulation of NF-κB pathway

PS Priya, R Murugan, BO Almutairi, S Arokiyaraj… - Environmental …, 2023 - Elsevier
Cadmium (Cd) exposure is known to cause gut inflammation. In this study, we investigated
the protective effects of cordycepin, a natural compound with pharmacological properties …