Immune responses regulated by cannabidiol

JM Nichols, BLF Kaplan - Cannabis and cannabinoid research, 2020 - liebertpub.com
Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …

Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age

JA Crippa, FS Guimarães, AC Campos… - Frontiers in …, 2018 - frontiersin.org
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

Beyond THC and endocannabinoids

P Pacher, NM Kogan… - Annual review of …, 2020 - annualreviews.org
Research in the cannabinoid field, namely on phytocannabinoids, the endogenous
cannabinoids anandamide and 2-arachidonoyl glycerol and their metabolizing and synthetic …

The antimicrobial effect behind Cannabis sativa

L Schofs, MD Sparo… - … Research & Perspectives, 2021 - Wiley Online Library
The development of multidrug‐resistant bacteria has revealed the need for new
antimicrobial compounds. Cannabis sativa preparations have a long history of medical …

[HTML][HTML] Early phase in the development of cannabidiol as a treatment for addiction: opioid relapse takes initial center stage

YL Hurd, M Yoon, AF Manini, S Hernandez, R Olmedo… - …, 2015 - Elsevier
Multiple cannabinoids derived from the marijuana plant have potential therapeutic benefits
but most have not been well investigated, despite the widespread legalization of medical …

Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I: C) rat model

AL Osborne, N Solowij, I Babic, XF Huang… - …, 2017 - nature.com
Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment,
including learning, memory and attention deficits. Antipsychotic drugs are limited in their …

A systematic review of the effect of cannabidiol on cognitive function: relevance to schizophrenia

AL Osborne, N Solowij, K Weston-Green - Neuroscience & Biobehavioral …, 2017 - Elsevier
Background and objectives Cognitive impairment is a core symptom domain of
schizophrenia, neurological disorders and substance abuse. It is characterised by deficits in …

[HTML][HTML] Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors

CHA Jesus, DDB Redivo, AT Gasparin, BB Sotomaior… - Brain research, 2019 - Elsevier
Most diabetic patients describe moderate to severe pain symptoms whose pharmacological
treatment is palliative and poorly effective. Cannabidiol (CBD) has shown promising results …

Cannabidiol: bridge between antioxidant effect, cellular protection, and cognitive and physical performance

G Jîtcă, BE Ősz, CE Vari, CM Rusz, A Tero-Vescan… - Antioxidants, 2023 - mdpi.com
The literature provides scientific evidence for the beneficial effects of cannabidiol (CBD), and
these effects extend beyond epilepsy treatment (eg, Lennox–Gastaut and Dravet …

The role of microglia activation in the development of sepsis-induced long-term cognitive impairment

M Michels, AS Vieira, F Vuolo, HG Zapelini… - Brain, behavior, and …, 2015 - Elsevier
Oxidative stress and inflammation is likely to be a major step in the development of sepsis-
associated encephalopathy (SAE) and long-term cognitive impairment. To date, it is not …