Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …
Flavonoids as anticancer agents
DM Kopustinskiene, V Jakstas, A Savickas… - Nutrients, 2020 - mdpi.com
Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …
Naringenin: A potential flavonoid phytochemical for cancer therapy
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …
Targeting the tumour vasculature: from vessel destruction to promotion
S Guelfi, K Hodivala-Dilke, G Bergers - Nature Reviews Cancer, 2024 - nature.com
As angiogenesis was recognized as a core hallmark of cancer growth and survival, several
strategies have been implemented to target the tumour vasculature. Yet to date, attempts …
strategies have been implemented to target the tumour vasculature. Yet to date, attempts …
Naringin and naringenin: Their mechanisms of action and the potential anticancer activities
J Stabrauskiene, DM Kopustinskiene, R Lazauskas… - Biomedicines, 2022 - mdpi.com
Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption
of which is beneficial for human health and has been practiced since ancient times …
of which is beneficial for human health and has been practiced since ancient times …
Extraction of flavonoids from natural sources using modern techniques
JO Chaves, MCA De Souza, LC Da Silva… - Frontiers in …, 2020 - frontiersin.org
Flavonoids are one of the main groups of polyphenols found in natural products. Traditional
flavonoid extraction techniques are being replaced by advanced techniques to reduce …
flavonoid extraction techniques are being replaced by advanced techniques to reduce …
Rutin: A flavonoid as an effective sensitizer for anticancer therapy; insights into multifaceted mechanisms and applicability for combination therapy
Rutin is a unique antioxidant flavonoid that is mainly found in fruit, vegetables, cereals, and
many other plant‐based human diets. This review aims to highlight the in vitro anticancer …
many other plant‐based human diets. This review aims to highlight the in vitro anticancer …
Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …
incidence rate and a huge burden on health care providers. DM is characterized by the …
Opportunities and challenges in enhancing the bioavailability and bioactivity of dietary flavonoids: A novel delivery system perspective
D Yuan, Y Guo, F Pu, C Yang, X **ao, H Du, J He, S Lu - Food Chemistry, 2024 - Elsevier
Flavonoids have multiple favorable bioactivities including antioxidant, anti-inflammatory, and
antitumor. Currently, flavonoid-containing dietary supplements are widely tested in clinical …
antitumor. Currently, flavonoid-containing dietary supplements are widely tested in clinical …
[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …
is characterized by hypercytokinemia, an exaggerated immune response associated with an …