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Carcinogenesis: Failure of resolution of inflammation?
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
Pentapeptide cRGDfK-surface engineered nanostructured lipid carriers as an efficient tool for targeted delivery of tyrosine kinase inhibitor for battling hepatocellular …
Background Antitumor research aims to efficiently target hepatocarcinoma cells (HCC) for
drug delivery. Nanostructured lipid carriers (NLCs) are promising for active tumour targeting …
drug delivery. Nanostructured lipid carriers (NLCs) are promising for active tumour targeting …
Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations
Purpose The application of betulinic acid (B), a potent antineoplastic agent, is limited due to
poor bioavailability, short plasma half-life and inappropriate tissue distribution. Thus, we …
poor bioavailability, short plasma half-life and inappropriate tissue distribution. Thus, we …
Vinpocetine mitigates DMH-induce pre-neoplastic colon damage in rats through inhibition of pro-inflammatory cytokines
Colorectal cancer (CRC) is currently recognized as the third most prevalent cancer
worldwide. Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine. It has been …
worldwide. Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine. It has been …
Inflammatory auxo-action in the stem cell division theory of cancer
Y Luo, JH **ao - PeerJ, 2023 - peerj.com
Acute inflammation is a beneficial response to the changes caused by pathogens or injuries
that can eliminate the source of damage and restore homeostasis in damaged tissues …
that can eliminate the source of damage and restore homeostasis in damaged tissues …
A novel quinazoline derivative exhibits potent anticancer cytotoxicity via apoptosis and inhibition of angiogenesis in DMBA‐induced mammary gland carcinoma
Mammary gland carcinoma is one of the most prevalent and deadly diseases among women
globally. It is a type of solid malignant tumor. In this malignant tumor, the microenvironment …
globally. It is a type of solid malignant tumor. In this malignant tumor, the microenvironment …
Assessments of in vitro and in vivo antineoplastic potentials of β-sitosterol-loaded PEGylated niosomes against hepatocellular carcinoma
Abstract β-sitosterol (BS), a phytosterol, exhibits ameliorative effects on hepatocellular
carcinoma (HCC) due to its antioxidant activities. However, its poor aqueous solubility and …
carcinoma (HCC) due to its antioxidant activities. However, its poor aqueous solubility and …
Preclinical Evaluation of Dimethyl Itaconate Against Hepatocellular Carcinoma via Activation of the e/iNOS-Mediated NF-κB–Dependent Apoptotic Pathway
Hepatocellular carcinoma (HCC) is one of the most common tumors affecting a large
population worldwide, with the fifth and seventh greatest mortality rates among men and …
population worldwide, with the fifth and seventh greatest mortality rates among men and …
The pharmacological effect of apricot seeds extracts and amygdalin in experimentally induced liver damage and hepatocellular carcinoma
A Ramadan, G Kamel, NE Awad… - Journal of …, 2020 - herbmedpharmacol.com
Abstract Introduction: Apricot (Prunus armeniaca L.) has been widely used for the treatment
of several disorders such as liver diseases, but the hepatoprotective and anticancer …
of several disorders such as liver diseases, but the hepatoprotective and anticancer …
[HTML][HTML] Ameliorative effect of fluvoxamine against colon carcinogenesis via COX-2 blockade with oxidative and metabolic stress reduction at the cellular, molecular …
Abstract Fluvoxamine's (FLX's) anticancer potential was investigated in pre-clinical research
utilizing a DMH-induced colorectal cancer (CRC) rat model. qRT-PCR and immunoblotting …
utilizing a DMH-induced colorectal cancer (CRC) rat model. qRT-PCR and immunoblotting …