[HTML][HTML] Alternative methods for testing botulinum toxin: Current status and future perspectives

MR Nepal, TC Jeong - Biomolecules & therapeutics, 2020 - ncbi.nlm.nih.gov
Botulinum toxins are neurotoxic modular proteins composed of a heavy chain and a light
chain connected by a disulfide bond and are produced by Clostridium botulinum. Although …

Optimization of Application-Driven Development of In Vitro Neuromuscular Junction Models

JB Strickland, K Davis-Anderson… - … Engineering Part B …, 2022 - liebertpub.com
Neuromuscular junctions (NMJs) are specialized synapses responsible for signal
transduction between motor neurons (MNs) and skeletal muscle tissue. Malfunction at this …

Critical analysis in the advancement of cell-based assays for botulinum neurotoxin

G Ambrin, S Cai, BR Singh - Critical Reviews in Microbiology, 2023 - Taylor & Francis
The study on botulinum neurotoxins (BoNTs) has rapidly evolved for their structure and
functions as opposed to them being poisons or cures. Since their discoveries, the scientific …

[HTML][HTML] Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics

JD de Lamotte, A Perrier, C Martinat… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Botulinum neurotoxins (BoNTs) are produced by Clostridium botulinum and are responsible
for botulism, a fatal disorder of the nervous system mostly induced by food poisoning …

Emerging Opportunities in Human Pluripotent Stem-Cells Based Assays to Explore the Diversity of Botulinum Neurotoxins as Future Therapeutics

J Duchesne de Lamotte, A Perrier, C Martinat… - International Journal of …, 2021 - mdpi.com
Botulinum neurotoxins (BoNTs) are produced by Clostridium botulinum and are responsible
for botulism, a fatal disorder of the nervous system mostly induced by food poisoning …

[CITA][C] Synthesis and evaluation of 7-substituted 3-propargylamine coumarin derivatives as multifunctional monoamine oxidase and cholinesterase inhibitors for …

SC Mzezewa - 2020 - University of Western Cape