Inherited epigenetic variation—revisiting soft inheritance

EJ Richards - Nature Reviews Genetics, 2006 - nature.com
Phenotypic variation is traditionally parsed into components that are directed by genetic and
environmental variation. The line between these two components is blurred by inherited …

Spontaneous mutation accumulation studies in evolutionary genetics

DL Halligan, PD Keightley - Annual Review of Ecology …, 2009 - annualreviews.org
Mutation accumulation (MA) experiments, in which mutations are allowed to drift to fixation in
inbred lines, have been a principal way of studying the rates and properties of new …

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing

H Lee, E Popodi, H Tang, PL Foster - … of the National Academy of Sciences, 2012 - pnas.org
Knowledge of the rate and nature of spontaneous mutation is fundamental to understanding
evolutionary and molecular processes. In this report, we analyze spontaneous mutations …

The Rate and Molecular Spectrum of Spontaneous Mutations in Arabidopsis thaliana

S Ossowski, K Schneeberger, JI Lucas-Lledó… - science, 2010 - science.org
To take complete advantage of information on within-species polymorphism and divergence
from close relatives, one needs to know the rate and the molecular spectrum of spontaneous …

An atlas of over 90,000 conserved noncoding sequences provides insight into crucifer regulatory regions

A Haudry, AE Platts, E Vello, DR Hoen, M Leclercq… - Nature …, 2013 - nature.com
Despite the central importance of noncoding DNA to gene regulation and evolution,
understanding of the extent of selection on plant noncoding DNA remains limited compared …

Mutation rate variation in multicellular eukaryotes: causes and consequences

CF Baer, MM Miyamoto, DR Denver - Nature Reviews Genetics, 2007 - nature.com
A basic knowledge about mutation rates is central to our understanding of a myriad of
evolutionary phenomena, including the maintenance of sex and rates of molecular …

Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …

V Katju, U Bergthorsson - Genome biology and evolution, 2019 - academic.oup.com
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Adaptive epigenetic memory of ancestral temperature regime in Arabidopsis thaliana

CA Whittle, SP Otto, MO Johnston, JE Krochko - Botany, 2009 - cdnsciencepub.com
Although certain acquired nongenetic (ie, epigenetic) traits are known to be heritable in
plants, little is known currently about whether environmental parameters can induce …

The evolution of sex: empirical insights into the roles of epistasis and drift

JAGM De Visser, SF Elena - Nature Reviews Genetics, 2007 - nature.com
Despite many years of theoretical and experimental work, the explanation for why sex is so
common as a reproductive strategy continues to resist understanding. Recent empirical work …

The conservation of wild plant species in seed banks: attention to both taxonomic coverage and population biology will improve the role of seed banks as conservation …

DJ Schoen, AHD Brown - BioScience, 2001 - academic.oup.com
There is abundant evidence that environments have shifted dramatically in biotic makeup
and climatic conditions during the recent geological past (Davis 1983, Pitelka and Plant …