Thyroid gland organogenesis results in an organ the shape, size, and position of which are
largely conserved among adult individuals of the same species, thus suggesting that genetic …

The molecular mechanisms that control regional specification, morphogenesis and
differentiation of the embryonic forebrain are not known, although recently seueral …

The 60-amino acid long homeodomain of Antennapedia crosses biological membranes by
an energy-independent mechanism, a phenomenon abolished by directed mutagenesis …

The thyroid-specific enhancer-binding protein (T/ebp) gene was disrupted by homologous
recombination in embryonic stem cells to generate mice lacking T/EBP expression …

Distinct classes of motor neurons and ventral interneurons are generated by the graded
signaling activity of Sonic hedgehog (Shh). Shh controls neuronal fate by establishing …

Pallial and subpallial morphological subdivisions of the develo** chicken telencephalon
were examined by means of gene markers, compared with their expression pattern in the …

The telencephalon is organized into distinct longitudinal domains: the cerebral cortex and
the basal ganglia. The basal ganglia primarily consists of a dorsal region (striatum) and a …

We have isolated two murine homeobox genes, Nkx-2. 5 and Nkx-2. 6, that are new
members of a sp sub-family of homeobox genes related to Drosophila NK2, NK3 and …

During development, basic helix–loop–helix (bHLH) proteins regulate formation of neurons
from multipotent progenitor cells. However, bHLH factors linked to gliogenesis have not …

We describe the cloning of insulin promoter factor 1 (IPF1), a homeodomain protein which in
the adult mouse pancreas is selectively expressed in the beta‐cells and which binds to and …