Transfusion of older stored blood and risk of death: a meta‐analysis

D Wang, J Sun, SB Solomon, HG Klein… - Transfusion, 2012 - Wiley Online Library
BACKGROUND: Blood for transfusion is stored for up to 42 days. Older blood develops
lesions and accumulates potentially injurious substances. Some studies report increasing …

Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients.

A Retter, D Wyncoll, R Pearse… - British journal of …, 2013 - search.ebscohost.com
The article offers information on the management of anaemia and red cell transfusion in
adult critically ill patients. It states that erythropoietin should not be used to treat anaemia in …

Effect of fresh red blood cell transfusions on clinical outcomes in premature, very low-birth-weight infants: the ARIPI randomized trial

DA Fergusson, P Hébert, DL Hogan, L LeBel… - Jama, 2012 - jamanetwork.com
Context Even though red blood cells (RBCs) are lifesaving in neonatal intensive care,
transfusing older RBCs may result in higher rates of organ dysfunction, nosocomial infection …

[HTML][HTML] Age of red cells for transfusion and outcomes in critically ill adults

DJ Cooper, ZK McQuilten, A Nichol, B Ady… - … England Journal of …, 2017 - Mass Medical Soc
Background It is uncertain whether the duration of red-cell storage affects mortality after
transfusion among critically ill adults. Methods In an international, multicenter, randomized …

Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non–transferrin-bound iron

EA Hod, GM Brittenham, GB Billote… - Blood, The Journal …, 2011 - ashpublications.org
Transfusions of RBCs stored for longer durations are associated with adverse effects in
hospitalized patients. We prospectively studied 14 healthy human volunteers who donated …

Metabolic influences modulating erythrocyte deformability and eryptosis

JF Brun, E Varlet-Marie, J Myzia… - Metabolites, 2021 - mdpi.com
Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …

Blood conservation in extracorporeal membrane oxygenation for acute respiratory distress syndrome

CL Agerstrand, KM Burkart, DC Abrams… - The Annals of thoracic …, 2015 - Elsevier
Background Extracorporeal membrane oxygenation support (ECMO) typically requires
multiple blood transfusions and is associated with frequent bleeding complications. Blood …

The pathophysiology and consequences of red blood cell storage

D Orlov, K Karkouti - Anaesthesia, 2015 - Wiley Online Library
Red cell transfusion therapy is a common treatment modality in contemporary medical
practice. Although blood collection and administration is safer and more efficient than ever …

Age of red blood cells and transfusion in critically ill patients

C Aubron, A Nichol, DJ Cooper, R Bellomo - Annals of intensive care, 2013 - Springer
Red blood cells (RBC) storage facilitates the supply of RBC to meet the clinical demand for
transfusion and to avoid wastage. However, RBC storage is associated with adverse …

Does prolonged storage of red blood cells cause harm?

WA Flegel, C Natanson, HG Klein - British journal of …, 2014 - Wiley Online Library
Red blood cells (RBC s) degrade progressively during the weeks of refrigerated storage. No
universally accepted definition of 'fresh'or 'old'RBC s exists. While practices vary from …