Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …

Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is
abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple …

The critical role of alpha-synuclein in Parkinson's disease represents a pivotal discovery.
Some progress has been made over recent years in identifying disease-modifying therapies …

Parkinson's disease (PD) is an age-related neurodegenerative disorder affecting millions of
people worldwide. The disease is characterized by the progressive loss of dopaminergic …

Many neurodegenerative diseases are characterized by abnormal protein aggregates,
including the two most common neurodegenerative diseases Alzheimer's disease (AD) and …

Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Parkinson's disease (PD) is a multifactorial disorder involving a complex interplay between a
variety of genetic and environmental factors. In this scenario, mitochondrial impairment and …

Advances in lipid nanoparticle (LNP) design have contributed notably to the emergence of
the current clinically approved mRNA-based vaccines and are of high relevance for …

The aggregation of alpha-synuclein (α-Syn) plays a critical role in the development of
Parkinson's disease (PD) and other synucleinopathies. α-Syn, which is encoded by the …

Protein condensation into liquid-like structures is critical for cellular compartmentalization,
RNA processing, and stress response. Research on protein condensation has primarily …