Convergent antibody responses to SARS-CoV-2 in convalescent individuals
During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory
syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people …
syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people …
Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
W Wen, W Su, H Tang, W Le, X Zhang, Y Zheng, X Liu… - Cell discovery, 2020 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people
and killed more than 60,000. The key immune cell subsets change and their states during …
and killed more than 60,000. The key immune cell subsets change and their states during …
Natural products with potential to treat RNA virus pathogens including SARS-CoV-2
Three families of RNA viruses, the Coronaviridae, Flaviviridae, and Filoviridae, collectively
have great potential to cause epidemic disease in human populations. The current SARS …
have great potential to cause epidemic disease in human populations. The current SARS …
Vesicular stomatitis virus: from agricultural pathogen to vaccine vector
G Liu, W Cao, A Salawudeen, W Zhu, K Emeterio… - Pathogens, 2021 - mdpi.com
Vesicular stomatitis virus (VSV), which belongs to the Vesiculovirus genus of the family
Rhabdoviridae, is a well studied livestock pathogen and prototypic non-segmented …
Rhabdoviridae, is a well studied livestock pathogen and prototypic non-segmented …
Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals
F Zhang, R Gan, Z Zhen, X Hu, X Li, F Zhou… - Signal transduction and …, 2020 - nature.com
The global Coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has
affected more than eight million people. There is an urgent need to investigate how the …
affected more than eight million people. There is an urgent need to investigate how the …
[HTML][HTML] Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients
C Kreer, M Zehner, T Weber, MS Ercanoglu… - Cell, 2020 - cell.com
The SARS-CoV-2 pandemic has unprecedented implications for public health, social life,
and the world economy. Because approved drugs and vaccines are limited or not available …
and the world economy. Because approved drugs and vaccines are limited or not available …
Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool
T Weber, S Dähling, S Rose, P Affeldt… - Science …, 2023 - science.org
The human immune response must continuously adapt to newly emerging SARS-CoV-2
variants. To investigate how B cells respond to repeated SARS-CoV-2 antigen exposure by …
variants. To investigate how B cells respond to repeated SARS-CoV-2 antigen exposure by …
Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants
M Korenkov, M Zehner, H Cohen-Dvashi… - Immunity, 2023 - cell.com
Somatic hypermutation (SHM) drives affinity maturation and continues over months in SARS-
CoV-2-neutralizing antibodies (nAbs). However, several potent SARS-CoV-2 antibodies …
CoV-2-neutralizing antibodies (nAbs). However, several potent SARS-CoV-2 antibodies …
Functional antibodies exhibit light chain coherence
The vertebrate adaptive immune system modifies the genome of individual B cells to encode
antibodies that bind particular antigens. In most mammals, antibodies are composed of …
antibodies that bind particular antigens. In most mammals, antibodies are composed of …
[HTML][HTML] Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals
Unrelated individuals can produce genetically similar clones of antibodies, known as public
clonotypes, which have been seen in responses to different infectious diseases, as well as …
clonotypes, which have been seen in responses to different infectious diseases, as well as …