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Glutamate and GABA homeostasis and neurometabolism in major depressive disorder
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
Diabetes and cognitive dysfunction
RJ McCrimmon, CM Ryan, BM Frier - The Lancet, 2012 - thelancet.com
Cognitive dysfunction in type 1 and type 2 diabetes share many similarities, but important
differences do exist. A primary distinguishing feature of type 2 diabetes is that people with …
differences do exist. A primary distinguishing feature of type 2 diabetes is that people with …
Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies
FS Luppino, LM de Wit, PF Bouvy… - Archives of general …, 2010 - jamanetwork.com
Context Association between obesity and depression has repeatedly been established. For
treatment and prevention purposes, it is important to acquire more insight into their …
treatment and prevention purposes, it is important to acquire more insight into their …
Impact of metabolic syndrome on cognition and brain: a selected review of the literature
KF Yates, V Sweat, PL Yau… - … , and vascular biology, 2012 - ahajournals.org
Metabolic syndrome (MetS), a clustering of risk factors for type 2 diabetes mellitus and
cardiovascular disease, has been associated with cognitive dysfunction and brain …
cardiovascular disease, has been associated with cognitive dysfunction and brain …
Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression
Inflammation and altered glutamate metabolism are two pathways implicated in the
pathophysiology of depression. Interestingly, these pathways may be linked given that …
pathophysiology of depression. Interestingly, these pathways may be linked given that …
The association between physical activity, fitness and body mass index on mental well-being and quality of life in adolescents
Purpose The purpose of the current study was to investigate the mediatory role between
vigorous physical activity, body mass index (BMI), and cardiorespiratory fitness on symptoms …
vigorous physical activity, body mass index (BMI), and cardiorespiratory fitness on symptoms …
Emerging role of glutamate in the pathophysiology of major depressive disorder
K Hashimoto - Brain research reviews, 2009 - Elsevier
Major depressive disorder (MDD) is a common, chronic, recurrent mental illness that affects
millions of individuals worldwide. To date, the monoaminergic systems (serotonin …
millions of individuals worldwide. To date, the monoaminergic systems (serotonin …
MR spectroscopic studies of the brain in psychiatric disorders
RJ Maddock, MH Buonocore - Brain imaging in behavioral neuroscience, 2012 - Springer
The measurement of brain metabolites with magnetic resonance spectroscopy (MRS)
provides a unique perspective on the brain bases of neuropsychiatric disorders. As a context …
provides a unique perspective on the brain bases of neuropsychiatric disorders. As a context …
Health‐related quality of life and fall risk associated with age‐related body composition changes; sarcopenia, obesity and sarcopenic obesity
ZA Öztürk, İH Türkbeyler, A Abiyev, S Kul… - Internal medicine …, 2018 - Wiley Online Library
Background Sarcopenia, obesity, and sarcopenic obesity are various features of the ageing
process that can cause important health issues. The present study was undertaken to …
process that can cause important health issues. The present study was undertaken to …
Altered spontaneous brain activity in type 2 diabetes: a resting-state functional MRI study
Y Cui, Y Jiao, YC Chen, K Wang, B Gao, S Wen… - Diabetes, 2014 - diabetesjournals.org
Previous research has shown that type 2 diabetes mellitus (T2DM) is associated with an
increased risk of cognitive impairment. Patients with impaired cognition often show …
increased risk of cognitive impairment. Patients with impaired cognition often show …