Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X **a… - Signal transduction and …, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

Next Generation RNA/Protein‐Carrying Vector With Pleiotropic Activity

T Nosaka, J Ohtsuka, T Ohtsuka… - Reviews in Medical …, 2024 - Wiley Online Library
Human parainfluenza virus type 2 (hPIV2), one of the causative agents of infantile common
cold, is a non‐segmented negative‐sense RNA virus with a robust gene expression system …

[HTML][HTML] Characterization of immune response diversity in rodents vaccinated with a vesicular stomatitis virus vectored COVID-19 vaccine

S Wang, C Zhang, B Liang, W Wang, N Feng, Y Zhao… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as the prime
challenge facing public health safety since 2019. Correspondingly, coronavirus disease …

[HTML][HTML] Immunogenicity and Protective Efficacy of a Single Intranasal Dose Vectored Vaccine Based on Sendai Virus (Moscow Strain) against SARS-CoV-2 Variant of …

GV Kochneva, GA Kudrov, SS Zainutdinov, IS Shulgina… - Vaccines, 2024 - mdpi.com
The mouse paramyxovirus Sendai, which is capable of limited replication in human
bronchial epithelial cells without causing disease, is well suited for the development of …

Current status of mucosal vaccines against SARS-CoV2: a hope for protective immunity

I García-Silva, DO Govea-Alonso… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The current vaccines used to fight against COVID-19 are effective, however the
induction of protective immunity is a pending goal required to prevent viral transmission …

Safety and efficacy of lentinan nasal drops in patients infected with the variant of COVID-19: a randomized, placebo-controlled trial

W Fan, B You, X Wang, X Zheng, A Xu, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Objective: Lentinan has antiviral, anti-tumor, immunomodulatory, stimulating interferon
production, and other pharmacological effects. Previous animal experiments have shown …

Multiple layers of innate immune response antagonism of SARS-CoV-2

F Zhou, S Periasamy, ND Jackson, WS Cheng… - bioRxiv, 2024 - biorxiv.org
Several SARS-CoV-2 proteins have been shown to counteract the host innate immune
response, mostly using in vitro protein expression, which may not fully reflect their role in the …

Intranasal vaccine against COVID-19 based on a recombinant variant of the Sendai virus (Paramyxoviridae: Respirovirus) strain Moscow

GA Kudrov, SS Zainutdinov, AA Grazhdantseva… - Problems of …, 2023 - virusjour.crie.ru
Introduction. Intranasal vaccination using live vector vaccines based on non-pathogenic or
slightly pathogenic viruses is the one of the most convenient, safe and effective ways to …

[PDF][PDF] Multiple layers of innate immune response antagonism of SARS-CoV-2

L Martinez-Sobrido, SC Sealfon - storage.prod.researchhub.com
ABSTRACT Several S RS-CoV-2 proteins have been shown to counteract the host innate
immune response, mostly using in vitro protein expression, which may not fully reflect their …