Periodontal diseases are highly prevalent chronic diseases, and severe periodontitis
creates functional and esthetic problems and decreases self‐esteem for a large percentage …

Melatonin is an uncommonly widely distributed molecule. It is found throughout the plant
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …

Oxygen is used by eukaryotic cells for metabolic transformations and energy production in
mitochondria. Under physiological conditions, there is a constant endogenous production of …

An important role for melatonin in bone formation and restructuring has emerged, and
studies demonstrate the multiple mechanisms for these beneficial actions. Statistical …

Background Diabetes mellitus (DM) and periodontitis are two common chronic diseases with
bidirectional relationship. Oxidative stress plays a key role in the pathogenesis of these two …

Hormetic dose responses are reported here to occur commonly in the dermal wound healing
process, with the particular focus on cell viability, proliferation, migration and collagen …

Melatonin plays an important role in regulating the sleep–wake cycle and adaptation to
environmental changes. Concentration measurements in bioliquids such as serum/plasma …

Aging-related salivary dysfunction commonly induces the poor oral health, including
decreased saliva flow and dental caries. Although the clinical significance of the salivary …

Oral and maxillofacial tissue defects caused by trauma, tumor reactions, congenital
anomalies, ischemic diseases, infectious diseases, surgical resection, and odontogenic …

Melatonin, an indole formed enzymatically from L-tryptophan, is the most versatile and
ubiquitous hormone molecule produced not only in all animals but also in some plants. This …