There are more than 100 recognized disorders of the eye. This makes the development of
advanced ocular formulations an important topic in pharmaceutical science. One of the ways …

Many new chemical entities are discovered with high therapeutic potential, however, many
of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility …

Over the last years, the scientific interest about topical ocular delivery targeting the posterior
segment of the eye has been increasing. This is probably due to the fact that this is a non …

Microbial keratitis is a severe, sight-threatening condition caused by various pathogens.
Eyedrops are the standard delivery modality for treating these disorders; however, blinking …

Olopatadine HCl is an antiallergic drug used for the management of allergic conjunctivitis.
Currently, it is delivered via eye drop solution, which is highly inefficient due to low …

Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised
lysosomal levels of cystine in the cells of all organs. It is treated by regular administration of …

Vision is necessary for a healthy and independentlife. Globally, about 2.2 billionindividuals
suffer from eye diseasesthat lead to visual impairment or blindness (WHO 2019), thus …

Chitosan oligosaccharide (C) was functionalized with l-arginine (A) and short hydrocarbon
chains (C 8) to design an amphiphilic copolymer, henceforth CAC 8, leading to …

Ocular drug delivery is hampered by blink action, dilution and washout by tears,
mechanisms of nasolacrimal drainage, and poor permeability of the cornea. This chapter …

O glaucoma é uma doença ocular neurodegenerativa com impacto substancial na saúde
pública, causando degeneração das células ganglionares da retina (CGR) e cegueira …