Ferroptosis in different pathological contexts seen through the eyes of mitochondria
Ferroptosis is a recently described form of regulated cell death characterized by intracellular
iron accumulation and severe lipid peroxidation due to an impaired cysteine‐glutathione …
iron accumulation and severe lipid peroxidation due to an impaired cysteine‐glutathione …
Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk
Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …
has confirmed that there are two types of adipose tissue with opposing functions: lipid …
Sex and species differences in the development of diet-induced obesity and metabolic disturbances in rodents
Prevalence and health consequences of obesity differ between men and women. Yet, most
preclinical studies investigating the etiology of obesity have, to date, been conducted in …
preclinical studies investigating the etiology of obesity have, to date, been conducted in …
Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles
Metabolomics may have the capacity to revolutionize disease diagnosis through the
identification of scores of metabolites that vary during environmental, pathogenic, or …
identification of scores of metabolites that vary during environmental, pathogenic, or …
[HTML][HTML] Regulation of energy metabolism pathways by estrogens and estrogenic chemicals and potential implications in obesity associated with increased exposure …
JQ Chen, TR Brown, J Russo - … et Biophysica Acta (BBA)-Molecular Cell …, 2009 - Elsevier
The prevalence of obesity among children, adolescents and adults has been dramatically
increasing worldwide during the last several decades. The obesity epidemic has been …
increasing worldwide during the last several decades. The obesity epidemic has been …
The glucocorticoid contribution to obesity
Obesity is fast becoming the scourge of our time. It is one of the biggest causes of death and
disease in the industrialized world, and affects as many as 32% of adults and 17% of …
disease in the industrialized world, and affects as many as 32% of adults and 17% of …
Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage
Objective: Gender and diet have an important effect in cardiovascular disease and other
aging-associated disorders, whose initiation and/or worsening seem to be delayed in …
aging-associated disorders, whose initiation and/or worsening seem to be delayed in …
[HTML][HTML] Regulation of mitochondrial respiratory chain structure and function by estrogens/estrogen receptors and potential physiological/pathophysiological …
JQ Chen, JD Yager, J Russo - … et Biophysica Acta (BBA)-Molecular Cell …, 2005 - Elsevier
It is well known that the biological and carcinogenic effects of 17β-estradiol (E2) are
mediated via nuclear estrogen receptors (ERs) by regulating nuclear gene expression …
mediated via nuclear estrogen receptors (ERs) by regulating nuclear gene expression …
[HTML][HTML] Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology
Reactive oxygen species (ROS) is a term that defines a group of unstable compounds
derived from exogenous sources or endogenous metabolism. Under physiological …
derived from exogenous sources or endogenous metabolism. Under physiological …
Gender dimorphism in rat liver mitochondrial oxidative metabolism and biogenesis
In the present study, we have investigated gender differences in rat liver mitochondrial
oxidative metabolism. Total mitochondrial population (M) as well as the heavy (M1), medium …
oxidative metabolism. Total mitochondrial population (M) as well as the heavy (M1), medium …