Molecular and nonmolecular diagnostic methods for invasive fungal infections

M Arvanitis, T Anagnostou, BB Fuchs… - Clinical microbiology …, 2014 - Am Soc Microbiol
Invasive fungal infections constitute a serious threat to an ever-growing population of
immunocompromised individuals and other individuals at risk. Traditional diagnostic …

Combination antifungal therapy

MD Johnson, C MacDougall… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The availability of new antifungal agents with novel mechanisms of action has stimulated
renewed interest in combination antifungal therapies. In particular, and despite the limited …

Liposomal amphotericin b as initial therapy for invasive mold infection: a randomized trial comparing a high–loading dose regimen with standard dosing (AmBiLoad …

OA Cornely, J Maertens, M Bresnik… - Clinical infectious …, 2007 - academic.oup.com
Background. Treatment of invasive mold infection in immunocompromised patients remains
challenging. Voriconazole has been shown to have efficacy and survival benefits over …

Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial

P Manzoni, M Rinaldi, S Cattani, L Pugni, MG Romeo… - Jama, 2009 - jamanetwork.com
Context Sepsis is a common and severe complication in premature neonates, particularly
those with very low birth weight (VLBW)(< 1500 g). Whether lactoferrin, a mammalian milk …

Galactomannan in bronchoalveolar lavage fluid: a tool for diagnosing aspergillosis in intensive care unit patients

W Meersseman, K Lagrou, J Maertens… - American journal of …, 2008 - atsjournals.org
Rationale: Invasive aspergillosis (IA) is an important cause of mortality in patients with
hematologic malignancies. However, IA appears to be gaining a foothold in the intensive …

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000

A Möricke, M Zimmermann… - Blood, The Journal …, 2016 - ashpublications.org
Induction therapy for childhood acute lymphoblastic leukemia (ALL) traditionally includes
prednisone; yet, dexamethasone may have higher antileukemic potency, leading to fewer …

Pneumocystis jirovecii Disease: Basis for the Revised EORTC/MSGERC Invasive Fungal Disease Definitions in Individuals Without Human Immunodeficiency Virus

K Lagrou, S Chen, H Masur, C Viscoli… - Clinical Infectious …, 2021 - academic.oup.com
Background Pneumocystis jirovecii pneumonia (PCP) causes substantive morbidity in
immunocompromised patients. The EORTC/MSGERC convened an expert group to …

Penicillium marneffei Infection: An Emerging Disease in Mainland China

Y Hu, J Zhang, X Li, Y Yang, Y Zhang, J Ma, L ** - Mycopathologia, 2013 - Springer
Penicillium marneffei is an emerging pathogenic fungus that can cause a life-threatening
systemic mycosis in immunocompromised hosts, especially in patients with AIDS. This …

Invasive aspergillosis in the intensive care unit

W Meersseman, K Lagrou, J Maertens… - Clinical infectious …, 2007 - academic.oup.com
Data regarding the incidence of invasive aspergillosis (IA) in the intensive care unit (ICU)
are scarce, and the incidence varies. An incidence of 5.8% in a medical ICU has been …

Voriconazole versus itraconazole for antifungal prophylaxis following allogeneic haematopoietic stem‐cell transplantation

DI Marks, A Pagliuca, CC Kibbler… - British journal of …, 2011 - Wiley Online Library
Antifungal prophylaxis for allogeneic haematopoietic stem‐cell transplant (alloHCT)
recipients should prevent invasive mould and yeast infections (IFIs) and be well tolerated …