[HTML][HTML] Nanostructured lipid carriers for delivery of chemotherapeutics: A review

M Haider, SM Abdin, L Kamal, G Orive - Pharmaceutics, 2020 - mdpi.com
The efficacy of current standard chemotherapy is suboptimal due to the poor solubility and
short half-lives of chemotherapeutic agents, as well as their high toxicity and lack of …

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of Controlled Release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier

VR Salvi, P Pawar - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Lipid nanocarriers are developed as an alternative to polymeric nanoparticles, liposomes
and emulsions. Further, Nanostructured Lipid Nanocarriers are the second generation lipid …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Multifunctional and stimuli-responsive nanocarriers for targeted therapeutic delivery

J Majumder, T Minko - Expert opinion on drug delivery, 2021 - Taylor & Francis
Introduction Nanocarrier-based delivery systems offer multiple benefits to overcome
limitations of the traditional drug dosage forms, such as protection of the drug, enhanced …

Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

MT Luiz, JSR Viegas, JP Abriata, F Viegas… - European Journal of …, 2021 - Elsevier
Nanotechnology has been widely applied to develop drug delivery systems to improve
therapeutic performance. The effectiveness of these systems is intrinsically related to their …

Micro‐nanocarriers based drug delivery technology for blood‐brain barrier crossing and brain tumor targeting therapy

L Wang, Y Shi, J Jiang, C Li, H Zhang, X Zhang… - Small, 2022 - Wiley Online Library
The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies

T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …

Transferrin-modified osthole PEGylated liposomes travel the blood-brain barrier and mitigate Alzheimer's disease-related pathology in APP/PS-1 mice

L Kong, X Li, Y Ni, H **ao, Y Yao, Y Wang… - International journal …, 2020 - Taylor & Francis
Introduction Osthole (Ost) is a coumarin compound that strengthens hippocampal neurons
and neural stem cells against Aβ oligomer-induced neurotoxicity in mice, and is a potential …