Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
X Tong, R Tang, M **ao, J Xu, W Wang… - Journal of hematology & …, 2022 - Springer
Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …
body against pathogenic substances. This process, called regulated cell death (RCD), is …
Mito‐bomb: targeting mitochondria for cancer therapy
X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Nanoparticle-induced ferroptosis: detection methods, mechanisms and applications
Although ferroptosis is an iron-dependent cell death mechanism involved in the
development of some severe diseases (eg, Parkinsonian syndrome, stroke and tumours) …
development of some severe diseases (eg, Parkinsonian syndrome, stroke and tumours) …
Current use of Fenton reaction in drugs and food
C Abe, T Miyazawa, T Miyazawa - Molecules, 2022 - mdpi.com
Iron is the most abundant mineral in the human body and plays essential roles in sustaining
life, such as the transport of oxygen to systemic organs. The Fenton reaction is the reaction …
life, such as the transport of oxygen to systemic organs. The Fenton reaction is the reaction …
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine
As an emerging cancer therapeutic target, non-apoptotic cell death such as ferroptosis,
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …
necroptosis and pyroptosis, etc., has revealed significant potential in cancer treatment for …
Recent advances in iron-complexes as drug candidates for cancer therapy: Reactivity, mechanism of action and metabolites
In this perspective, we discuss iron-complexes as drug candidates that are promising
alternatives to conventional platinum-based chemotherapies owing to their broad range of …
alternatives to conventional platinum-based chemotherapies owing to their broad range of …
Recent progress on nanomedicine-induced ferroptosis for cancer therapy
The current treatment strategies for cancer therapy have posed many problems in achieving
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …
Ferroptosis in cancer therapeutics: a materials chemistry perspective
Q Guan, LL Zhou, YB Dong - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Ferroptosis, distinct from apoptosis, is a regulated form of cell death caused by lipid
peroxidation that has attracted extensive research interest since it was first defined in 2012 …
peroxidation that has attracted extensive research interest since it was first defined in 2012 …
Redox-regulating nanotherapeutics potentiating ferroptosis-driven cancer treatment
X Yang, X Sun, J Lei, X Shi, S Zhang, C Luo - Chemical Engineering …, 2024 - Elsevier
Ferroptosis has garnered considerable attention benefiting from its remarkable potential in
fighting malignant tumors. Its occurrence largely relies the overwhelming accumulation of …
fighting malignant tumors. Its occurrence largely relies the overwhelming accumulation of …
Mitochondria-targeting chemodynamic therapy nanodrugs for cancer treatment
Q Chen, N Li, X Wang, Y Yang, Y **ang… - Frontiers in …, 2022 - frontiersin.org
Mitochondria, as one of the most critical subcellular organelles of cancer cells, are very
vulnerable and often on the verge of oxidative stress. The classic chemodynamic therapy …
vulnerable and often on the verge of oxidative stress. The classic chemodynamic therapy …