Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

Despite advances in treatment, cancer remains a leading cause of death worldwide.
Although treatment strategies are continually progressing, cancers have evolved many …

Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …

Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer
therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis …

Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

Immunotherapy is one of the promising strategies in the treatment of oncology. Immune
checkpoint inhibitors, as a type of immunotherapy, have no significant efficacy in the clinical …

Inducing a full antitumor immune response in the tumor microenvironment (TME) is essential
for successful cancer immunotherapy. Here, we report that an oncolytic adenovirus carrying …

Despite the fact that the new drugs and targeted therapies have been approved for cancer
therapy during the past 30 years, the majority of cancer types are still remain challenging to …

MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by
inhibiting the translation of target transcripts. The expression profiles of miRNAs vary in …

Researchers have tried to find novel strategies for cancer treatment in the past decades.
Among the utilized methods, administering oncolytic viruses (OVs) alone or combined with …