Abstract Rosai-Dorfman-Destombes disease (RDD) is a rare non–Langerhans cell
histiocytosis characterized by accumulation of activated histiocytes within affected tissues …

Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK …

Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

Erdheim-Chester disease (ECD) is a rare, potentially fatal multiorgan myeloid neoplasm
occurring mainly in adults. The diagnosis is established by clinical, radiologic, and histologic …

Histiocytoses are disorders characterised by inflammation and the accumulation of cells
derived from the monocyte and macrophage lineages, which results in tissue damage …

Abstract The Kasabach-Merritt phenomenon (KMP) in kaposiform hemangioendothelioma
(KHE) is characterized by life-threatening thrombocytopenia and consumptive coagulopathy …

Erdheim-Chester disease (ECD) is characterized by the infiltration of tissues by foamy
CD68+ CD1a− histiocytes, with 1500 known cases since 1930. Mutations activating the …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Erdheim-Chester disease (ECD) and Rosai-Dorfman disease (RDD) are rare non-
Langerhans cell histiocytoses (non-LCHs), for which therapeutic options are limited. MAPK …

Erdheim–Chester disease (ECD) is a rare non-Langerhans cell histiocytosis with a putative
neoplastic and inflammatory nature. The disease is driven by mutations in proto-oncogenes …