Transition from inflammation to proliferation: a critical step during wound healing

NX Landén, D Li, M Ståhle - Cellular and Molecular Life Sciences, 2016‏ - Springer
The ability to rapidly restore the integrity of a broken skin barrier is critical and is the ultimate
goal of therapies for hard-to-heal-ulcers. Unfortunately effective treatments to enhance …

Wound repair and regeneration: mechanisms, signaling, and translation

SA Eming, P Martin, M Tomic-Canic - Science translational medicine, 2014‏ - science.org
The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

[HTML][HTML] The relationship between circulating testosterone and inflammatory cytokines in men

NV Mohamad, SK Wong, WNW Hasan, JJ Jolly… - The Aging …, 2019‏ - Taylor & Francis
Testosterone is the predominant gonadal androgen in men. Low testosterone levels are
found to be associated with an increased in metabolic risk and systematic inflammation …

Steroidogenesis in the skin: implications for local immune functions

A Slominski, B Zbytek, G Nikolakis, PR Manna… - The Journal of steroid …, 2013‏ - Elsevier
The skin has developed a hierarchy of systems that encompasses the skin immune and
local steroidogenic activities in order to protect the body against the external environment …

Inflammatory markers in women with polycystic ovary syndrome

E Rudnicka, M Kunicki, K Suchta… - BioMed research …, 2020‏ - Wiley Online Library
Several studies have reported the association between polycystic ovary syndrome (PCOS)
and low‐grade chronic inflammation to be of uncertain cause: obesity, insulin resistance, or …

Sexual hormones in human skin

CC Zouboulis, WC Chen, MJ Thornton… - Hormone and …, 2007‏ - thieme-connect.com
The skin locally synthesizes significant amounts of sexual hormones with intracrine or
paracrine actions. The local level of each sexual steroid depends upon the expression of …

The role of androgens in women's health and wellbeing

VE Bianchi, E Bresciani, R Meanti, L Rizzi… - Pharmacological …, 2021‏ - Elsevier
Androgens in women, as well as in men, are intrinsic to maintenance of (i) reproductive
competency,(ii) cardiac health,(iii) appropriate bone remodeling and mass retention,(iii) …

The role of androgen and androgen receptor in skin-related disorders

JJ Lai, P Chang, KP Lai, L Chen, C Chang - Archives of dermatological …, 2012‏ - Springer
Androgen and androgen receptor (AR) may play important roles in several skin-related
diseases, such as androgenetic alopecia and acne vulgaris. Current treatments for these …

RETRACTED: Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial

J McCoy, A Goren, FA Cadegiani… - Frontiers in …, 2021‏ - frontiersin.org
Antiandrogens have demonstrated a protective effect for COVOD-19 patients in
observational and interventional studies. The goal of this study was to determine if …

[HTML][HTML] Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice

JJ Lai, KP Lai, W Zeng, KH Chuang, S Altuwaijri… - The American journal of …, 2012‏ - Elsevier
Upon insult, such as infection or tissue injury, the innate and adaptive immune systems
initiate a series of responses to defend the body. Recent studies from immune cell-specific …