Alkenylation of arenes and heteroarenes with alkynes

VP Boyarskiy, DS Ryabukhin, NA Bokach… - Chemical …, 2016 - ACS Publications
This review is focused on the analysis of current data on new methods of alkenylation of
arenes and heteroarenes with alkynes by transition metal catalyzed reactions …

Recent advances in the chemistry of pentafulvenes

P Preethalayam, KS Krishnan, S Thulasi… - Chemical …, 2017 - ACS Publications
Pentafulvenes are a unique class of compounds that originally attracted attention due to
their propensity to display nonbenzenoid aromaticity. Subsequently, they were recognized …

A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53

A Ghosh, A Sengupta, GPK Seerapu, A Nakhi… - Biochemical and …, 2017 - Elsevier
The NAD+-dependent protein deacetylase SIRT1 has emerged as an important target for
epigenetic therapeutics of colon cancer as its increased expression is associated with …

Use of AlCl 3 in Friedel Crafts arylation type reactions and beyond: an overview on the development of unique methodologies leading to N-heteroarenes

R Sunke, SB Nallapati, JS Kumar, KS Kumar… - Organic & Biomolecular …, 2017 - pubs.rsc.org
As a privileged class of heterocyclic compounds N-heteroarenes have found enormous
applications in many areas including medicinal/pharmaceutical chemistry and drug …

Advances in Transition‐Metal‐Catalysed Alkyne Hydroarylations

A Biffis, C Tubaro, M Baron - The Chemical Record, 2016 - Wiley Online Library
We present herein a personal account of our achievements in the development of novel
catalytic systems based on late‐transition‐metal complexes for the hydroarylation of …

Effect of Aqueous Polyethylene Glycol on 1, 3‐Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2‐Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles …

R Gangadhara Chary… - Advanced Synthesis …, 2014 - Wiley Online Library
Abstract A 1: 1 mixture of water‐polyethylene glycol (PEG) facilitated the 1, 3‐dipolar
cycloaddition of benzoylnitromethane/ethyl 2‐nitroacetate with terminal alkynes or alkenes …

A sonochemical approach to 4-substituted pyrrolo [1, 2-a] quinoxalines via Cu-catalyzed N-arylation followed by Wang resin/air promoted oxidative cyclization strategy

R Chemboli, BT Mandava, US Kodali, AK Taneja… - Tetrahedron …, 2024 - Elsevier
Abstract The 4-substituted pyrrolo [1, 2-a] quinoxaline framework was explored for the
identification of possible inhibitors of SIRT1. To access the target compounds a general and …

Wang-OSO3H catalyzed green synthesis of 2-arylamino-3-cyanopyridine derivatives under ultrasound: Their assessment as potential inhibitors of SIRT1

CS Challa, NK Katari, V Nallanchakravarthula… - Journal of Molecular …, 2022 - Elsevier
New approaches/strategies to develop potential anticancer agents are necessary not only to
address the increasing incidences of cancer worldwide but also to overcome the …

Sonochemical thiocyanation of pyrrolo [1, 2-a] quinoxalines: Identification of potential inhibitors of SIRT1

M Baldha, J Shivanoori, SK Kolli, R Kapavarapu… - Journal of Molecular …, 2024 - Elsevier
A series of compounds based on the 1-thiocyanatopyrrolo [1, 2-a] quinoxaline framework
were designed and assessed as potential inhibitors of SIRT1. A convenient access to this …

Sonochemical synthesis of 2-substituted nicotinic acid ethyl ester derivatives: Their in vitro and in silico evaluation against SIRT1

CS Challa, NK Katari, V Nallanchakravarthula… - Journal of Molecular …, 2021 - Elsevier
Based on the initial docking studies of a representative compound in silico the evaluation of
SIRT1 inhibitory potential of 2-substituted nicotinic acid ethyl ester derivatives was …