The study of autoimmunity mediated by immunoglobulin E (IgE) autoantibodies, which may
be termed autoallergy, is in its infancy. It is now recognized that systemic lupus …

The prevalence of allergy to furry animals has been increasing, and allergy to cats, dogs, or
both is considered a major risk factor for the development of asthma and rhinitis. An …

Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

The availability of allergen molecules ('components') from several protein families has
advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled …

Odorant‐binding proteins (OBPs) of vertebrates belong to the lipocalin superfamily and
perform a dual function: solubilizing and ferrying volatile pheromones to the olfactory …

Many allergens feature hydrophobic cavities that allow the binding of primarily hydrophobic
small‐molecule ligands. Ligand‐binding specificities can be strict or promiscuous. Serum …

Component-resolved diagnostics (CRD) utilize purified native or recombinant allergens to
detect IgE sensitivity to individual allergen molecules and have become of growing …

Environmental assessment and exposure control is different from other practice parameters
developed by the Joint Task Force on Practice Parameters in a number of important ways …

A large number of allergens have been discovered but we know little about their potential to
induce inflammation (allergenic activity) and symptoms. Nowadays, the clinical importance …

Background Allergy to the domestic dog (C anis familiaris) affects 5–10% of the population
in affluent countries. Three of four patients are allergic to more than one pet, which can only …