Influenza A viruses remain a global threat to human health, with continued pandemic
potential. In this Review, we discuss our current understanding of the optimal immune …

Sepsis is a life-threatening systemic inflammatory response syndrome caused by the host
imbalanced response to infection. Lung injury is the most common complication of sepsis …

Globally, plastics are used in various products. Concerns regarding the human body's
exposure to plastics and environmental pollution have increased with increased plastic use …

Excessive inflammation and tissue damage during severe influenza A virus (IAV) infection
can lead to the development of fatal pulmonary disease. Pyroptosis is a lytic and pro …

Rationale Severe viral respiratory infections are often characterised by extensive myeloid
cell infiltration and activation and persistent lung tissue injury. However, the immunological …

Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
present life-threatening conditions characterized by inflammation and endothelial injury …

Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …

Gasdermins (GSDMs) are a class of pore-forming proteins related to pyroptosis, a
programmed cell death pathway that is induced by a range of inflammatory stimuli. Small …

Sepsis-induced acute respiratory distress syndrome (ARDS) has high morbidity and
mortality, and it has three major pathogeneses, namely alveolar–capillary barrier …

Influenza viruses are one of the major causes of human respiratory infections and the newly
emerging and re-emerging strains of influenza virus are the cause of seasonal epidemics …