Background Ewing's sarcoma (ES) is an aggressive cancer of bone and soft tissue, most of
which tend to occur in the bone. Extraosseous Ewing's sarcoma (EES) of the cervix is …

Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive sarcoma driven by the
EWSR1:: WT1 chimeric transcription factor. Despite this unique oncogenic driver, DSRCT …

Identification of mutations in histones in a number of human neoplasms and developmental
syndromes represents the most compelling evidence to date for a causal role of epigenetic …

Background In certain rare undifferentiated small round cell sarcomas new specific
molecular CIC‐DUX4/other partner, BCOR‐CCNB3/other partner, YWHAE fusions, or BCOR …

Recurrent gene fusions (GFs) in translocated sarcomas are recognized as major oncogenic
drivers of the disease, as well as diagnostic markers whose identification is necessary for …

Ewing sarcoma (EWS) is an aggressive pediatric bone tumor characterized by unmet clinical
needs and an incompletely understood epigenetic heterogeneity. Here, we considered …

Ewing sarcomas (ESs) are biologically aggressive tumours of bone and soft tissues caused
by chromosomal translocations yielding in-frame fusion proteins driving the neoplastic …

Ewing sarcoma, the second most prevalent malignant bone tumor with potential occurrence
in soft tissues, exhibits a high level of aggressiveness, primarily afflicting children and …

Simple Summary Fusion proteins are an important class of oncogenes in sarcoma.
Approximately 40 percent of all sarcoma entities are driven by one of the more than 100 …

Abstract Desmoplastic Small Round Cell Tumor (DSRCT) is a rare, pediatric cancer caused
by the EWSR1:: WT1 fusion protein. DSRCT predominantly occurs in males, which comprise …