Forensic DNA Phenoty**: Predicting human appearance from crime scene material for investigative purposes

M Kayser - Forensic Science International: Genetics, 2015 - Elsevier
Forensic DNA Phenoty** refers to the prediction of appearance traits of unknown sample
donors, or unknown deceased (missing) persons, directly from biological materials found at …

The contribution of Neanderthal introgression to modern human traits

PF Reilly, A Tjahjadi, SL Miller, JM Akey, S Tucci - Current Biology, 2022 - cell.com
Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

Human genetic history on the Tibetan Plateau in the past 5100 years

H Wang, MA Yang, S Wangdue, H Lu, H Chen, L Li… - Science …, 2023 - science.org
Using genome-wide data of 89 ancient individuals dated to 5100 to 100 years before the
present (BP) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry …

Genome-wide patterns of selection in 230 ancient Eurasians

I Mathieson, I Lazaridis, N Rohland, S Mallick… - Nature, 2015 - nature.com
Ancient DNA makes it possible to observe natural selection directly by analysing samples
from populations before, during and after adaptation events. Here we report a genome-wide …

The genetic history of ice age Europe

Q Fu, C Posth, M Hajdinjak, M Petr, S Mallick… - Nature, 2016 - nature.com
Modern humans arrived in Europe~ 45,000 years ago, but little is known about their genetic
composition before the start of farming~ 8,500 years ago. Here we analyse genome-wide …

The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation

L Chaitanya, K Breslin, S Zuñiga, L Wirken… - Forensic Science …, 2018 - Elsevier
Abstract Forensic DNA Phenoty** (FDP), ie the prediction of human externally visible traits
from DNA, has become a fast growing subfield within forensic genetics due to the …

A high-coverage genome sequence from an archaic Denisovan individual

M Meyer, M Kircher, MT Gansauge, H Li, F Racimo… - Science, 2012 - science.org
We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …

Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements

LW Barrett, S Fletcher, SD Wilton - Cellular and molecular life sciences, 2012 - Springer
There is now compelling evidence that the complexity of higher organisms correlates with
the relative amount of non-coding RNA rather than the number of protein-coding genes …

Pleistocene North African genomes link near Eastern and sub-Saharan African human populations

M Van de Loosdrecht, A Bouzouggar, L Humphrey… - Science, 2018 - science.org
North Africa is a key region for understanding human history, but the genetic history of its
people is largely unknown. We present genomic data from seven 15,000-year-old modern …

Physiological functions of the HECT family of ubiquitin ligases

D Rotin, S Kumar - Nature reviews Molecular cell biology, 2009 - nature.com
The ubiquitylation of proteins is carried out by E1, E2 and E3 (ubiquitin ligase) enzymes, and
targets them for degradation or for other cellular fates. The HECT enzymes, including Nedd4 …