Poststroke cognitive impairment and dementia (PSCID) is a major source of morbidity and
mortality after stroke worldwide. PSCID occurs as a consequence of ischemic stroke …

Women face a disproportionate burden of stroke mortality and disability. Biologic sex and
sociocultural gender both contribute to differences in stroke risk factors, assessment …

Importance Stroke is the fifth leading cause of death and a leading cause of disability in the
United States, affecting nearly 800 000 individuals annually. Observations Sudden …

Objectives: Concise “synthetic” review of the state of the art of management of acute
ischemic stroke. Data Sources: Available literature on PubMed. Study Selection: We …

Importance Whether intravenous thrombolysis is needed in combination with mechanical
thrombectomy in patients with acute large vessel occlusion stroke is unclear. Objective To …

Importance Tirofiban is a highly selective nonpeptide antagonist of glycoprotein IIb/IIIa
receptor, which reversibly inhibits platelet aggregation. It remains uncertain whether …

Importance Whether recent changes in demographic characteristics and therapeutic
technologies have altered stroke outcomes remains unknown. Objective To determine …

Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

Importance Preclinical and clinical studies have suggested a neuroprotective effect of
remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on …

The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …