Intracerebral hemorrhage is a devastating disease. Despite its clinical importance, the
pathophysiology of intracerebral hemorrhage is not well understood. Hematoma expansion …

Intracerebral hemorrhage (ICH) is a major health concern, with high rates of mortality and
morbidity and no highly effective clinical interventions. Basic research in animal models of …

Intracerebral hemorrhage (ICH) is a devastating form of stroke affecting millions of people
worldwide. Parenchymal hematoma triggers a series of reactions leading to primary and …

Iron overload plays a key role in the secondary brain damage that develops after
intracerebral hemorrhage (ICH). The significant increase in iron deposition is associated …

Background: Disturbance of brain iron metabolism after intracerebral hemorrhage (ICH)
results in oxidative brain injury and cognition impairment. Hepcidin plays an important role …

Inhibition of histone deacetylases (HDACs) has been shown to reduce inflammation and
white matter damage after various forms of brain injury via modulation of …

Spontaneous intracerebral hemorrhage (ICH) accounts for 15% of all stroke cases. ICH is a
devastating form of stroke associated with high morbidity, mortality, and disability. Preclinical …

Background and Purpose Inflammasome‐mediated pyroptosis is an important neuronal cell
death mechanism. Previous studies reported that activation of melanocortin MC4 receptor …

Background: There are limited data on the trajectory of recovery and long-term functional
outcomes after intracerebral hemorrhage (ICH). Most ICH trials have conventionally …

Intracerebral hemorrhage (ICH), the most lethal type of stroke, often leads to poor outcomes
in the clinic. Due to the complex mechanisms and cell–cell crosstalk during ICH, the …