Mechanisms, evaluation, and management of chronic constipation

AE Bharucha, BE Lacy - Gastroenterology, 2020 - Elsevier
With a worldwide prevalence of 15%, chronic constipation is one of the most frequent
gastrointestinal diagnoses made in ambulatory medicine clinics, and is a common source …

Understanding the physiology of human defaecation and disorders of continence and evacuation

PT Heitmann, PF Vollebregt, CH Knowles… - Nature reviews …, 2021 - nature.com
The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Advances in the evaluation of anorectal function

EV Carrington, SM Scott, A Bharucha, F Mion… - Nature reviews …, 2018 - nature.com
Faecal incontinence and evacuation disorders are common, impair quality of life and incur
substantial economic costs worldwide. As symptoms alone are poor predictors of underlying …

First translational consensus on terminology and definitions of colonic motility in animals and humans studied by manometric and other techniques

M Corsetti, M Costa, G Bassotti, AE Bharucha… - Nature Reviews …, 2019 - nature.com
Alterations in colonic motility are implicated in the pathophysiology of bowel disorders, but
high-resolution manometry of human colonic motor function has revealed that our …

Low anterior resection syndrome

TH Nguyen, RV Chokshi - Current gastroenterology reports, 2020 - Springer
Abstract Purpose of Review Low anterior resection syndrome is a highly prevalent condition
that can develop after anal sphincter-sparing surgery for rectal cancer and impair quality of …

Review of the indications, methods, and clinical utility of anorectal manometry and the rectal balloon expulsion test

AE Bharucha, G Basilisco, A Malcolm… - …, 2022 - Wiley Online Library
Background Anorectal manometry (ARM) comprehensively assesses anorectal
sensorimotor functions. Purpose This review examines the indications, techniques …

Gastrointestinal dysfunction after spinal cord injury

GM Holmes, EN Blanke - Experimental neurology, 2019 - Elsevier
The gastrointestinal tract of vertebrates is a heterogeneous organ system innervated to
varying degrees by a local enteric neural network as well as extrinsic parasympathetic and …

[HTML][HTML] Pelvic floor dysfunction

WR Grimes, M Stratton - 2020 - europepmc.org
Pelvic Floor Dysfunction - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Management of low anterior resection syndrome (LARS) following resection for rectal cancer

H Rosen, CG Sebesta, C Sebesta - Cancers, 2023 - mdpi.com
Simple Summary The present narrative review aims to give an overview about the causes
and the management of low anterior resection syndrome, a common postoperative …

Pregnancy and postpartum bowel changes: constipation and fecal incontinence

GH Shin, EL Toto, R Schey - … journal of the American College of …, 2015 - journals.lww.com
Pregnancy and the postpartum period are often associated with many gastrointestinal
complaints, including nausea, vomiting, and heartburn; however, the most troublesome …