Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a …
RJ Kim, RC Becker - American heart journal, 2003 - Elsevier
BACKGROUND: The association between the inherited gene mutations of factor V,
prothrombin, and homocysteine metabolism and venous thromboembolic events is accepted …
prothrombin, and homocysteine metabolism and venous thromboembolic events is accepted …
Thrombophilia as a multigenic disease
BACKGROUND AND OBJECTIVE: Venous thrombosis is a common disease annually
affecting 1 in 1000 individuals. The multifactorial nature of the disease is illustrated by the …
affecting 1 in 1000 individuals. The multifactorial nature of the disease is illustrated by the …
Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism
Factor V Leiden and factor II G20210A mutations are two frequent genetic risk factors
involved in venous thromboembolism (VTE). The goal of this pooled analysis of 8 case …
involved in venous thromboembolism (VTE). The goal of this pooled analysis of 8 case …
“Normal” Thrombin Generation: Presented in part at the XVIth Congress of the International Society on Thrombosis and Haemostasis, June 6-12, 1997, Florence, Italy …
S Butenas, C van't Veer… - Blood, The Journal of the …, 1999 - ashpublications.org
We have investigated the influence of alterations in plasma coagulation factor levels
between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX …
between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX …
G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men
PM Ridker, CH Hennekens, JP Miletich - Circulation, 1999 - Am Heart Assoc
Background—A single base pair mutation in the prothrombin gene has recently been
identified that is associated with increased prothrombin levels. Whether this mutation …
identified that is associated with increased prothrombin levels. Whether this mutation …
High prevalence of osteonecrosis of the femoral head in HIV-infected adults
KD Miller, H Masur, EC Jones, GO Joe… - Annals of internal …, 2002 - acpjournals.org
Background: Osteonecrosis has been reported to occur occasionally among HIV-infected
patients. The diagnosis of symptomatic osteonecrosis of the hip in two of the authors' …
patients. The diagnosis of symptomatic osteonecrosis of the hip in two of the authors' …
Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review
SM Boekholdt, NR Bijsterveld, AHM Moons, M Levi… - Circulation, 2001 - Am Heart Assoc
Background—It is pathophysiologically conceivable that genetic variations in coagulation
and fibrinolytic proteins are associated with the risk of myocardial infarction. Methods and …
and fibrinolytic proteins are associated with the risk of myocardial infarction. Methods and …
Single and combined prothrombotic factors in patients with idiopathic venous thromboembolism: prevalence and risk assessment
O Salomon, DM Steinberg, A Zivelin… - … , and vascular biology, 1999 - Am Heart Assoc
The inherited thrombophilias—deficiencies of protein C, protein S, and antithrombin III—and
the prothrombotic polymorphisms factor V G1691A and factor II G20210A predispose …
the prothrombotic polymorphisms factor V G1691A and factor II G20210A predispose …
Interaction between the G20210A mutation of the prothrombin gene and oral contraceptive use in deep vein thrombosis
I Martinelli, E Taioli, P Bucciarelli… - … , and vascular biology, 1999 - Am Heart Assoc
Single-point mutations in the gene coding for prothrombin (factor II: A20210) or factor V
(factor V: A1691) are associated with an increased risk of venous thromboembolism. The …
(factor V: A1691) are associated with an increased risk of venous thromboembolism. The …
Diagnostic testing for coagulopathies in patients with ischemic stroke
CD Bushnell, LB Goldstein - Stroke, 2000 - Am Heart Assoc
Background—Hypercoagulable states are a recognized, albeit uncommon, etiology of
ischemic stroke. It is unclear how often the results of specialized coagulation tests affect …
ischemic stroke. It is unclear how often the results of specialized coagulation tests affect …