Engineering and functionalization of gelatin biomaterials: From cell culture to medical applications

AB Bello, D Kim, D Kim, H Park… - Tissue Engineering Part B …, 2020 - liebertpub.com
Health care and medicine were revolutionized in recent years by the development of
biomaterials, such as stents, implants, personalized drug delivery systems, engineered …

Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications

S Sart, AC Tsai, Y Li, T Ma - Tissue Engineering Part B: Reviews, 2014 - liebertpub.com
Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …

A simple bioreactor-based method to generate kidney organoids from pluripotent stem cells

A Przepiorski, V Sander, T Tran, JA Hollywood… - Stem Cell Reports, 2018 - cell.com
Kidney organoids made from pluripotent stem cells have the potential to revolutionize how
kidney development, disease, and injury are studied. Current protocols are technically …

A scalable system for production of functional pancreatic progenitors from human embryonic stem cells

TC Schulz, HY Young, AD Agulnick, MJ Babin… - PloS one, 2012 - journals.plos.org
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will
require the translation of proof-of-principle concepts into a scalable, controlled, and …

Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications

MC Decarli, R Amaral, DP Dos Santos, LB Tofani… - …, 2021 - iopscience.iop.org
Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …

Oxygenation in cell culture: Critical parameters for reproducibility are routinely not reported

A Al-Ani, D Toms, D Kondro, J Thundathil, Y Yu… - PloS one, 2018 - journals.plos.org
Mammalian cell culture is foundational to biomedical research, and the reproducibility of
research findings across the sciences is drawing increasing attention. While many …

Specificity of 3D MSC spheroids microenvironment: impact on MSC behavior and properties

A Jauković, D Abadjieva, D Trivanović… - Stem cell reviews and …, 2020 - Springer
Mesenchymal stem cells (MSC) have been considered the promising candidates for the
regenerative and personalized medicine due to their self-renewal potential, multilineage …

Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm

ES Lippmann, CE Williams, DA Ruhl, MC Estevez-Silva… - Stem cell reports, 2015 - cell.com
Colinear HOX expression during hindbrain and spinal cord development diversifies and
assigns regional neural phenotypes to discrete rhombomeric and vertebral domains …

A 3D magnetic tissue stretcher for remote mechanical control of embryonic stem cell differentiation

V Du, N Luciani, S Richard, G Mary, C Gay… - Nature …, 2017 - nature.com
The ability to create a 3D tissue structure from individual cells and then to stimulate it at will
is a major goal for both the biophysics and regenerative medicine communities. Here we …

[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …