Organoselenium compounds as mimics of selenoproteins and thiol modifier agents

NV Barbosa, CW Nogueira, PA Nogara… - Metallomics, 2017 - academic.oup.com
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …

Synthesis and antioxidant properties of organoselenium compounds

R Mamgain, M Kostic, FV Singh - Current Medicinal Chemistry, 2023 - benthamdirect.com
Background: The chemistry of organoselenium reagents provides an asset for organic
synthesis. The versatility of these reagents as electrophiles and nucleophiles makes them …

Design and synthesis of diselenobisbenzamides (DISeBAs) as nucleocapsid protein 7 (NCp7) inhibitors with anti-HIV activity

L Sancineto, A Mariotti, L Bagnoli, F Marini… - Journal of medicinal …, 2015 - ACS Publications
The interest in the synthesis of Se-containing compounds is growing with the discovery of
derivatives exhibiting various biological activities. In this manuscript, we have identified a …

Probing the superiority of diselenium bond on docetaxel dimeric prodrug nanoassemblies: small roles taking big responsibilities

S Zuo, B Sun, Y Yang, S Zhou, Y Zhang, M Guo, M Sun… - Small, 2020 - Wiley Online Library
The current state of chemotherapy is far from satisfaction, restricted by the inefficient drug
delivery and the off‐target toxicity. Prodrug nanoassemblies are emerging as efficient …

Small Organoselenium Compounds: More than just Glutathione Peroxidase Mimics.

T Wirth - Angewandte Chemie International Edition, 2015 - search.ebscohost.com
Small Organoselenium Compounds: More than just Glutathione Peroxidase Mimics Page 1
German Edition: DOI: 10.1002/ange.201505056 Antioxidants International Edition: DOI …

Selenocompounds in cancer therapy: an overview

D Bartolini, L Sancineto, AF de Bem, KD Tew… - Advances in cancer …, 2017 - Elsevier
In vitro and in vivo experimental models clearly demonstrate the efficacy of Se compounds
as anticancer agents, contingent upon chemical structures and concentrations of test …

Global soil distribution, dietary access routes, bioconversion mechanisms and the human health significance of selenium: A review

JN Ekumah, Y Ma, NDK Akpabli-Tsigbe, E Kwaw, S Ma… - Food Bioscience, 2021 - Elsevier
Selenium (Se) is a required micronutrient with numerous health implications for all life forms.
Organic Se species are considered nutritionally beneficial since they are highly bioavailable …

Design and preparation of a polymer resin-supported organoselenium catalyst with industrial potential

Y Wang, L Yu, B Zhu, L Yu - Journal of Materials Chemistry A, 2016 - pubs.rsc.org
Hexavalent Se? Yes! Selenium on polymers exhibits quite different properties compared to
that in small molecules. Hexavalent Se, rare in organoselenium chemistry, was found to be …

Coordination chemistry and synthetic approaches of pyridyl-selenium ligands: A decade update

R Cargnelutti, RF Schumacher, AL Belladona… - Coordination Chemistry …, 2021 - Elsevier
Pyridyl-selenium compounds have been extensively studied due to their applications in
different areas of knowledge, especially in pharmacology, material science and technology …

Synthesis and antioxidant property of novel 1, 2, 3-triazole-linked starch derivatives via 'click chemistry'

W Tan, Q Li, W Li, F Dong, Z Guo - International Journal of Biological …, 2016 - Elsevier
Based on the copper (I) catalyzed Huisgen azide-alkyne cycloaddition (click chemistry), the
novel synthesis of a variety of 1, 2, 3-triazole-linked starch derivatives was developed …