Toxicity of lead: a review with recent updates

G Flora, D Gupta, A Tiwari - Interdisciplinary toxicology, 2012 - sciendo.com
Lead poisoning has been recognized as a major public health risk, particularly in
develo** countries. Though various occupational and public health measures have been …

Chelation in metal intoxication

SJS Flora, V Pachauri - … journal of environmental research and public …, 2010 - mdpi.com
Chelation therapy is the preferred medical treatment for reducing the toxic effects of metals.
Chelating agents are capable of binding to toxic metal ions to form complex structures which …

[HTML][HTML] The detrimental effects of lead on human and animal health

MA Assi, MNM Hezmee, MYM Sabri, MA Rajion - Veterinary world, 2016 - ncbi.nlm.nih.gov
Lead, a chemical element in the carbon group with symbol Pb (from Latin: Plumbum,
meaning “the liquid silver”) and has an atomic number 82 in the periodic table. It was the first …

Arsenic-induced oxidative stress and its reversibility

SJS Flora - Free Radical Biology and Medicine, 2011 - Elsevier
This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Heavy metal induced oxidative stress & its possible reversal by chelation therapy

SJS Flora, M Mittal, A Mehta - Indian Journal of Medical Research, 2008 - journals.lww.com
Exposure to heavy metals is a common phenomenon due to their environmental
pervasiveness. Metal intoxication particularly neurotoxicity, genotoxicity, or carcinogenicity is …

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure

SJS Flora - Oxidative medicine and cellular longevity, 2009 - Wiley Online Library
Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid.
Beneficial renal effects of some medications, such as chelation therapy depend at least …

Neurotoxicity linked to dysfunctional metal ion homeostasis and xenobiotic metal exposure: redox signaling and oxidative stress

C Garza-Lombó, Y Posadas, L Quintanar… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

Environmental toxicity, oxidative stress and apoptosis: menage a trois

R Franco, R Sánchez-Olea, EM Reyes-Reyes… - … /Genetic Toxicology and …, 2009 - Elsevier
Apoptosis is an evolutionary conserved homeostatic process involved in distinct
physiological processes including organ and tissue morphogenesis, development and …

Indigofera oblongifolia Prevents Lead Acetate-Induced Hepatotoxicity, Oxidative Stress, Fibrosis and Apoptosis in Rats

AE Abdel Moneim - PLoS One, 2016 - journals.plos.org
The current study was aimed to evaluate the preventive effects of Indigofera oblongifolia leaf
extract (IOLE) on lead acetate (PbAc)-induced hepatotoxicity in adult male Wistar rats. PbAc …

Interaction of 24-epibrassinolide and salicylic acid regulates pigment contents, antioxidative defense responses, and gene expression in Brassica juncea L. seedlings …

SK Kohli, N Handa, A Sharma, V Gautam… - … Science and Pollution …, 2018 - Springer
Lead (Pb) is considered one the most hazardous pollutant, and its accumulation in soil and
plants is of prime concern. To understand the role of plant hormones in combating heavy …