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Platelet-rich plasma: new performance understandings and therapeutic considerations in 2020
Emerging autologous cellular therapies that utilize platelet-rich plasma (PRP) applications
have the potential to play adjunctive roles in a variety of regenerative medicine treatment …
have the potential to play adjunctive roles in a variety of regenerative medicine treatment …
NF‐κB signaling in inflammation and cancer
T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …
in 1986, extraordinary efforts have been made to understand the function and regulating …
Programmed cell death detection methods: a systematic review and a categorical comparison
S Kari, K Subramanian, IA Altomonte, A Murugesan… - Apoptosis, 2022 - Springer
Programmed cell death is considered a key player in a variety of cellular processes that
helps to regulate tissue growth, embryogenesis, cell turnover, immune response, and other …
helps to regulate tissue growth, embryogenesis, cell turnover, immune response, and other …
Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics
Several studies have utilized a lipid nanoparticle delivery system to enhance the
effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are …
effectiveness of mRNA therapeutics and vaccines. However, these nanoparticles are …
[HTML][HTML] Cell death
Cell death supports morphogenesis during development and homeostasis after birth by
removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating …
removing damaged or obsolete cells. It also curtails the spread of pathogens by eliminating …
Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment
L Wang, Y Liu, Y Dai, X Tang, T Yin, C Wang, T Wang… - Gut, 2023 - gut.bmj.com
Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma
(PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune …
(PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune …
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment
Y Wu, S Wan, S Yang, H Hu, C Zhang, J Lai… - Journal of …, 2022 - Springer
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted
therapy, but their simple biological functionalization is still a challenging task against the …
therapy, but their simple biological functionalization is still a challenging task against the …
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
L Vande Walle, M Lamkanfi - Nature Reviews Drug Discovery, 2024 - nature.com
Diseases associated with chronic inflammation constitute a major health burden across the
world. As central instigators of the inflammatory response to infection and tissue damage …
world. As central instigators of the inflammatory response to infection and tissue damage …
Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms
Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …
Myeloid-derived suppressor cells coming of age
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells
generated during a large array of pathologic conditions ranging from cancer to obesity …
generated during a large array of pathologic conditions ranging from cancer to obesity …