Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

This review summarizes the theory of zeta potential (ZP) and the most relevant data about
how it has been used for studying bacteria. We have especially focused on the discovery …

BP100 is a short cationic antimicrobial peptide with a mechanism of action dependent on
peptide–lipid interactions and microbial surface charge neutralization. Although active …

Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …

Cell-penetrating peptides (CPP) are able to efficiently transport cargos across cell
membranes without being cytotoxic to cells, thus present a great potential in drug delivery …

LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped
viruses at non-cytotoxic concentrations (IC50≤ 0.5 µM), and was posited to exploit the …

Fungal infections with high mortality rates represent an increasing health risk. The
Neosartorya (Aspergillus) fischeri antifungal protein 2 (NFAP2) is a small, cysteine-rich …

Many cellular phenomena occur on the biomembranes. There are plenty of molecules
(natural or xenobiotics) that interact directly or partially with the cell membrane …

Infections caused by Gram-negative bacteria, Escherichia coli and Pseudomonas
aeruginosa foremost among them, constitute a major worldwide health problem …

Peptide-membrane interactions play a key role in the mechanisms of activity of antimicrobial
peptides. Here, methods of fluorescence spectroscopy, zeta potential, and molecular …