A guide for the diagnosis of rare and undiagnosed disease: beyond the exome
Rare diseases affect 30 million people in the USA and more than 300–400 million
worldwide, often causing chronic illness, disability, and premature death. Traditional …
worldwide, often causing chronic illness, disability, and premature death. Traditional …
Network pharmacology approach for medicinal plants: review and assessment
Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …
DGIdb 3.0: a redesign and expansion of the drug–gene interaction database
The drug–gene interaction database (DGIdb, www. dgidb. org) consolidates, organizes and
presents drug–gene interactions and gene druggability information from papers, databases …
presents drug–gene interactions and gene druggability information from papers, databases …
Integrated omics: tools, advances and future approaches
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …
Machine learning and integrative analysis of biomedical big data
Recent developments in high-throughput technologies have accelerated the accumulation
of massive amounts of omics data from multiple sources: genome, epigenome …
of massive amounts of omics data from multiple sources: genome, epigenome …
Cloud computing for genomic data analysis and collaboration
B Langmead, A Nellore - Nature Reviews Genetics, 2018 - nature.com
Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …
large sequencing data sets are growing in number, and public archives for raw sequencing …
DGIdb 2.0: mining clinically relevant drug–gene interactions
Abstract The Drug–Gene Interaction Database (DGIdb, www. dgidb. org) is a web resource
that consolidates disparate data sources describing drug–gene interactions and gene …
that consolidates disparate data sources describing drug–gene interactions and gene …
A review of bioinformatic pipeline frameworks
J Leipzig - Briefings in bioinformatics, 2017 - academic.oup.com
High-throughput bioinformatic analyses increasingly rely on pipeline frameworks to process
sequence and metadata. Modern implementations of these frameworks differ on three key …
sequence and metadata. Modern implementations of these frameworks differ on three key …
Survey on multi-omics, and multi-omics data analysis, integration and application
MH Shahrajabian, W Sun - Current Pharmaceutical Analysis, 2023 - benthamdirect.com
Multi-omics approaches have developed as a profitable technique for plant systems, a
popular method in medical and biological sciences underlining the necessity to outline new …
popular method in medical and biological sciences underlining the necessity to outline new …
Using phenocams to monitor our changing Earth: toward a global phenocam network
Rapid changes to the biosphere are altering ecological processes worldwide. Develo**
informed policies for mitigating the impacts of environmental change requires an …
informed policies for mitigating the impacts of environmental change requires an …