3D bioprinting for cartilage and osteochondral tissue engineering

AC Daly, FE Freeman… - Advanced …, 2017 - Wiley Online Library
Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

Photo-cross-linkable hyaluronic acid bioinks for bone and cartilage tissue engineering applications

F Ghorbani, B Ghalandari… - International …, 2023 - journals.sagepub.com
Hyaluronic acid (HA) is of immense importance to biomaterials science and biomedical
engineering. It is finding applications in diverse areas of bioengineering ranging from …

Reinforcement of hydrogels using three-dimensionally printed microfibres

J Visser, FPW Melchels, JE Jeon… - Nature …, 2015 - nature.com
Despite intensive research, hydrogels currently available for tissue repair in the
musculoskeletal system are unable to meet the mechanical, as well as the biological …

Yield stress determines bioprintability of hydrogels based on gelatin-methacryloyl and gellan gum for cartilage bioprinting

VHM Mouser, FPW Melchels, J Visser, WJA Dhert… - …, 2016 - iopscience.iop.org
Bioprinting of chondrocyte-laden hydrogels facilitates the fabrication of constructs with
controlled organization and shape eg for articular cartilage implants. Gelatin-methacryloyl …

The mechanobiology of articular cartilage: bearing the burden of osteoarthritis

J Sanchez-Adams, HA Leddy, AL McNulty… - Current rheumatology …, 2014 - Springer
Articular cartilage injuries and degenerative joint diseases are responsible for progressive
pain and disability in millions of people worldwide, yet there is currently no treatment …

Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair

J Kisiday, M **, B Kurz, H Hung… - Proceedings of the …, 2002 - National Acad Sciences
Emerging medical technologies for effective and lasting repair of articular cartilage include
delivery of cells or cell-seeded scaffolds to a defect site to initiate de novo tissue …

Scaffold mean pore size influences mesenchymal stem cell chondrogenic differentiation and matrix deposition

A Matsiko, JP Gleeson, FJ O'Brien - Tissue Engineering Part A, 2015 - liebertpub.com
Recent investigations into micro-architecture of scaffolds has revealed that mean pore sizes
are cell-type specific and influence cellular shape, differentiation, and extracellular matrix …

Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies

VC Mow, XE Guo - Annual review of biomedical engineering, 2002 - annualreviews.org
▪ Abstract In this chapter, the recent advances in cartilage biomechanics and
electromechanics are reviewed and summarized. Our emphasis is on the new experimental …

Structure and function of articular cartilage and meniscus

VC Mow, WY Gu, FH Chen - Basic orthopaedic biomechanics …, 2005 - books.google.com
Cartilage is a soft connective tissue that is composed of a single cell type, chondrocyte, and
a highly specialized extracellular matrix (ECM). Three major types of cartilaginous tissues …

[HTML][HTML] In vitro and in vivo investigation of a zonal microstructured scaffold for osteochondral defect repair

JAM Steele, AC Moore, JP St-Pierre, SD McCullen… - Biomaterials, 2022 - Elsevier
Articular cartilage is comprised of zones that vary in architecture, extracellular matrix
composition, and mechanical properties. Here, we designed and engineered a porous zonal …