While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …

Zinc homeostatic medicine is of great potential for cancer chemo‐immunotherapy; however,
there are few reports on antitumor compounds that can trigger Zn2+‐mediated immune …

The intestinal microbiota is well known to have multiple benefits on human health, including
cancer prevention and treatment. The effects are partially mediated by microbiota-produced …

Platinum (II)-based drugs are widely used for the treatment of solid tumors, especially in
combination protocols. Severe side effects and occurrence of resistance are the major …

A series of triple action Pt (IV) prodrugs was designed to test the hypothesis that multi-action
compounds, where each bioactive moiety intervenes in several cellular processes, might be …

The concept of multi-action octahedral platinum (IV) complexes is based on the rational
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …

To overcome the side effects of and resistance to cisplatin, a variety of Pt (IV) prodrugs were
designed and synthesized via different modifications including combination with lipid chains …

Platinum (IV) complexes are particularly appealing as prodrugs since their relative inertness,
and consequent low toxicity outside the cell is matched by their high activity inside the tumor …

A set of nickel (II) and copper (II) complexes incorporated anthracenyl hydrazone ligands
were synthesized and characterized with the help of various spectroscopic techniques …