Assay devices designed for these applications offer improvements to existing methods or
provide fundamentally new strategies. Both mature methods and novel techniques have …

Antibody technology has transformed drug development, providing robust approaches to
producing highly targeted and active therapeutics that can routinely be advanced through …

Identification of cancer cell–surface biomarkers and advances in antibody engineering have
led to a sharp increase in the development of therapeutic antibodies. These same advances …

The increased demand for molecular imaging tracers useful in assessing and monitoring
diseases has stimulated research towards more efficient and flexible radiosynthetic routes …

Extracellular vesicles are nano-to micro-scale, membrane-bound particles released by cells
into extracellular space, and act as carriers of biomarkers and therapeutics, holding …

Noninvasive prenatal diagnosis (NIPD) aims to detect fetal-related genetic disorders before
birth by detecting markers in the peripheral blood of pregnant women, holding the potential …

Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has
attracted increasing interest within the last decade. The technical advantages of …

Hepatocellular carcinoma (HCC) is an increasingly lethal malignancy for which
management is critically dependent on accurate imaging. Glypican-3 (GPC3) is a cell …

Pancreatic cancer has a high mortality rate due to late diagnosis and the tendency to invade
surrounding tissues and metastasize at an early stage. A molecular imaging agent that …

The exquisite specificity of antibodies and antibody fragments renders them excellent agents
for targeted delivery of radionuclides. Radiolabeled antibodies and fragments have been …