Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Organoid culture has been extensively exploited for normal tissue reconstruction and
disease modeling. However, it is still challenging to establish organoids that mimic in vivo …

Epithelial branch elongation is a central developmental process during branching
morphogenesis in diverse organs. This fundamental growth process into large arborized …

Cell packing—the spatial arrangement of cells—determines the shapes of organs. Recently,
investigations of organ development in a variety of model organisms have uncovered …

Cell motility is a widespread biological property that is best understood in the context of
individual cell migration. Indeed, studies of migration in culture have provided tremendous …

Branching morphogenesis is an evolutionary solution to maximize epithelial function in a
compact organ. It involves successive rounds of branch elongation and branch point …

The mammary epithelium is composed of an inner luminal and surrounding myoepithelial
cell layer. The presence of cancer cells beyond the myoepithelium defines invasive breast …

Mammary gland development occurs mainly after birth and is composed of three successive
stages: puberty, pregnancy and lactation, and involution. These developmental stages are …

During branching morphogenesis, a simple cluster of cells proliferates and branches to
generate an arborized network that facilitates fluid flow. The overall architecture of the …