Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …

Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range
of applications. During recent years, one of the most challenging goals is the development of …

Diabetic wound repair and skin regeneration remains a worldwide challenge due to the
impaired functionality of re-vascularization. Methods: This study reports a bioactive self …

Recanalization therapy is increasingly used in the treatment of acute ischemic stroke.
However, in about one third of these patients, recanalization is followed by …

Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Brain injuries affect a large patient population with major physical and emotional suffering
for patients and their relatives; at a significant cost to the society. Effective diagnostic and …

Rationale: Cerebral ischemia upregulates aquaporin-4 expression, increases blood-brain
barrier (BBB) permeability, and induces brain edema. Mesenchymal stem cells (MSCs) can …

From the global perspective, stroke refers to a highly common cause of disability and death.
Ischemic stroke (IS), attributed to blood vessel blockage, preventing the flow of blood to …

Quantitatively tracking engraftment of intracerebrally or intravenously transplanted stem cells
and evaluating their concomitant therapeutic efficacy for stroke has been a challenge in the …

Current studies demonstrated that metformin is not only a hypoglycemic drug, but also a
neuro-protective agent. However, the effect of metformin during ischemic brain injury is …